In addition to being an outcome of dysglycemia, the presence of one disease state may be a harbinger for, or exacerbate, another. This insight elevates the constellation of comorbid conditions of hyperglycemia from a theoretical construct to a bona fide, practical management tool and objective [...
Middle School is a time of separating the wheat from the chaff academically and I established myself as one of the sensitive achievers, making me a hero to burnouts and metalheads everywhere who were at the time generally regarded as dumb. I was artistic and had good relationships with girls...
et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1, 555–567 (2007). Article CAS PubMed PubMed Central Google Scholar Carpentino, J. E. et al. Aldehyde dehydrogenase-expressing colon stem cells ...
So, what is the cause of this damage? It can be the outcome of intense inflammatory responses associated with immune dysregulation, direct infection of immune cells, or autoimmune reactions (Dandekar and Perlman, 2005). Although the exact immune mechanism that brings about mortality among COVID-...
Numerous clinical studies have established that the presence and enrichment of tumor-infiltrating T lymphocytes (TILs) in solid tumors is highly associated with better outcome in cancer patients.6,7,8,9,10 Importantly, tumors with enriched TILs (hot tumors) are highly receptive to immunotherapy comp...
When glucose enters a cell, it is phosphorylated, giving the molecule a negative charge. This traps the molecule in the cell and is the first of 10 reactions of glycolysis, which produces pyruvate and ATP. Aerobic respiration (the Krebs cycle and the ele
Fermentation is any metabolic process in which the presence of microorganisms causes a needed outcome in food or beverages. It can be found in yeast and bacteria and oxygen-depleted muscle cells, as in lactic acid fermentation. It is used to improve flavor, preserve foods, and provide health ...
A fundamental requirement for the successful management of these tumours is the use of appropriate imaging methods for accurate disease detection and characterization. In this context, due to the increased glucose uptake and glycolysis of most cancer cells, metabolic imaging on a combined positron ...
What one word in the patient's chart note gives the answer to how the patient's insulin was administered? Drug Administration: Drug administration can occur via many different routes. Drugs will be administered in the method that is best for maximal a...
These findings together highlight the importance of adequate oxygen delivery to the placenta for healthy pregnancy outcome. Animal models of placental hypoxia can give insight into the effects of high altitude on pregnancy and the importance of oxygen in both normal placental development and the ...