MAPK signaling pathway and endometriosis: what is the link? [J]. Arch Gynecol Obstet , 2013, 287 ( 4 ) : 837 - 838.Mormile,R.,Vittori,G.. MAPK signaling pathway and endometriosis: What is the link?[J].Archives of gynecology and obstetrics 2013,4(4)....
MapISNet MAPISO MAPIT MAPIU MAPJ MAPK MAPK/ERK MAPK/ERK2 MAPK1 MAPK13 MAPK8 MAPK9 MAPKAP MAPKAPK MAPKAPK2 MAPKAPK3 MAPKI MAPKK MAPKK1 MAPKKK MAPKKKK5 MAPKP MAPL MAPLA MAPLD MAPLE MAPLE-DW MAPLIC MAPLR MAPLS MAPLV MAPM
(21,22) MAPKs are phosphorylated and activated by MAPK-kinases (MAPKKs or MAP2Ks), which in turn are phosphorylated and activated by MAPKK-kinases (MAPKKK or MAP3Ks). Differential gene expressions of the MAPK signaling pathway in enterovirus 71-infected rhabdomyosarcoma cells "Tomato 14-3-3 ...
In the present paper, we review recent advances in our understanding of IE gene transcription, chiefly focusing on FOS and its activation by ERK (extracellular-signal-regulated kinase) MAPK (mitogen-activated protein kinase) pathway signalling. We highlight important fundamental regulatory principles, ...
Usually, the activation of TLRs leads to downstream intracellular signaling. The MAPK pathway is one of the main signaling cascades associated with TLRs stimulation, and it is composed of the extracellular, signal-related kinases 1 and 2 (ERK 1/2), p38 MAPK and c-jun NH2-terminal kinase (...
The MAPK signaling pathway comprises 4 distinct cascades, designated as extracellular signal regulated kinases 1/2 (ERK1/2), Jun amino-terminal kinases 1/2/3 (JNK1/2/3), p38-MAPK, and extracellular signal regulated kinase 5 (ERK5), according to their most downstream kinase tier. Mitogen-Act...
Kaempferol attenuates cardiac hypertrophy via regulation of ASK1/MAPK signaling pathway and oxidative stress. Planta Medica, 2017, 83(10), 837–845 Kashafi, E., Moradzadeh, M., Mohamadkhani, A., & Erfanian, S. Kaempferol increases apoptosis in human cervical cancer HeLa cells via PI3K/AKT ...
Inflammatory Bowel Disease (IBD) is a chronic inflammatory disease with relapse and remission periods. Ulcerative colitis and Crohn’s disease are two major forms of the disease. IBD imposes a lot of sufferings on the patient and has many consequences; however, the most important is the increased...
Interestingly, regulation of GSK3 by the canonical Wnt signaling pathway does not involve N-terminal or tyrosine phosphorylation [21]. Wnt regulation of GSK3 is most likely achieved through disruption of a specific complex including Axin/APC/β-catenin and GSK3 (Figure 1). This mechanism ha...
BRAF, part of the MAPK pathway, has been shown to be mutated in 8% of newly diagnosed MM patients and mostly consists of the V600E variant (46%) but also has mutational hotspots at G466, G469, and D594 [41]. Based on studies in melanoma [44], these mutations can either be kinase...