A study, led by the Institute of Cancer Research in London, discovered a new drug class could, in mice, kill brain cancer cells with mutations in the ACVR1 gene, associated with DIPG, and shrink tumours. New hope for child brain cancer The family are trying to raise PS73,000 with the...
For the cardiomyocyte, the spectrum of dedifferentiation is characterised by a wide range of changes at the levels of gene expression, proteins, morphology and function, arguably more accurately called cellular plasticity. Nevertheless, when differentiated cells “revert” to exhibiting a progenitor cell...
1. Introduction The mitochondrion is an essential organelle conserved in eukaryotic organisms, which conducts several key biological functions. The primary function of mitochondria is to manufacture ATP, the major energy resource of the cells, through oxidative respiration reactions [1]. In addition, ...
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While there is a great overlap of currently described populations, some progenitor subsets, especially those at distinct skeletal locations, also differ by their surface marker or gene expression, the ability to support the HSC niche, their osteochondroadipogenic or osteochondrogenic potency, and the ...