not tissue- or cell-specific, this approach may not be sufficient to determine the specific tissue in which the expression is detected [7]. To overcome these challenges, the ideal solution is the isolation of specific tissues. In the case of secondary growth, it is possible to manually separa...
This arises due to the utilization of alternative promoters, and is further compounded by significant variability with regards to the precise transcriptional start sites of each (not to mention alternative splicing). Consequently, the transcript for a protein coding gene is not a unique mRNA, but ...
The molecular characterization of poorly and anaplastic thyroid carcinomas has been greatly improved in the last years following the advent of high through
Several molecularisoforms of Growth Hormone (GH) exist in the pituitary gland and are released to blood. In particular, a variant of approximately 20 kDa originated by an alternative splicing is present in a rather constant 1:9 ratio, while recently an additional variant of ~ 23-24 kDa has ...
Polymorphisms in natural resistance-associated macrophage protein 1 (NRAMP1), toll-like receptor 2 (TLR2), interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α), interleukin-1 receptor antagonist (IL-1RA), IL-10, vitamin D receptor (VDR), dendritic cell-specific ICAM-3-grabbing non-...
The expression of fibroblast activation protein in clear cell renal cell carcinomas is associated with synchro- nous lymph node metastases. PLoS ONE. 2016;11(12):13. 13. Sun LY, Ke ML, Wang X, Yin MY, Wei JN, Xu L, Tian X, Wang F, Zhang H, Fu SB, Zhang CY. FAP(high) alpha...
doi:10.1093/pcp/pcy199Ya-Wen HsuChien-Ta JuanChung-Min WangGuang-Yuh JauhOxford Academic
KY Sarkisova,IS Midzianovskaia,MA Kulikov - 《Philosophy》 被引量: 29发表: 2002年 The 5' Leader of the mRNA Encoding the Marek's Disease Virus Serotype 1 pp14 Protein Contains an Intronic Internal Ribosome Entry Site with Allosteric Prop... Transcribed as a 1.8-kb family of immediate-ear...
Gene expression, the connection between the information encoded within a gene and the final functional protein, is the central concept of molecular biology. This complex, multistaged, highly regulated process involves the transcription of genes into mRNA followed by their translation into proteins [6,...
[67]. The reason underpinning this exquisite sensitivity relates to the multitude of protein targets for H+ions. The significance of this observation is that only a small change in pHe is sufficient to produce a meaningful effect on cell behaviours. Thus, among competing cell populations, the ...