Perler, F. B. & Adam, E. (2000) Protein splicing and its applications. Curr. Opin. Biotechnol., 377-383.Perler FB, Adam E (2000) Protein splicing and its applications. Curr Opin Biotechnol 11:377-383Perler F B ,Adam E. Protein Splicing and its Applications. Curr Opin Biotech ,2000 ...
Protein-splicing reaction via a thiazolidine intermediate: Crystal structure of the VMA1-derived endonuclease bearing the N and C-terminal propeptides 2002, Journal of Molecular Biology Show abstract Dissecting the chemistry of protein splicing and its applications 2000, Angewandte Chemie - International...
What is RNA splicing?DNA and RNANucleic AcidsPolymerase Chain Reaction (PCR)ProteinRNAPosted on June 22, 2020What are the three major steps in mRNA processing?DNADNA and RNAPolymerase Chain Reaction (PCR)ProteinRNAPosted on June 22, 2020
protein splicing with enzyme-mediated peptide ligation. We show that this approach can be used to introduce PTMs and biochemical probes into a range of proteins including Cas9 nuclease and the transcriptional regulator MeCP2, which causes Rett syndrome when mutated. The versatility of the approach ...
revealed, for example, that the shortest lifetime group in the cortex is enriched for proteins involved in the regulation of RNA splicing and helicase activity, while clusters of stable proteins correspond to myelin, mitochondria, and structurally stable elements such as the cytoskeleton and nuclear ...
Moreover,S. cerevisiaecan express heterologous proteins as up to 49.3% (w/w) of its own protein [5].S. cerevisiaehas been commonly documented to produce heterologous proteins, and its current status is summarized in Table1. It has been widely used for producing medicinal proteins, food protei...
Alternative splicing regulation by interaction of phosphatase PP2Cgamma with nucleic acid-binding protein YB-1 Nat. Structural Mol. Biol, 14 (2007), pp. 630-638 Google Scholar 48. Khoronenkova S.V., Dianova I.I., Ternette N., Kessler B.M., Parsons J.L., Dianov G.L. ATM-dependent...
RNA regulation is significantly dependent on its binding protein partner, known as the RNA-binding proteins (RBPs). Unfortunately, the binding preferences for most RBPs are still not well characterized. Interdependencies between sequence and secondary st
Neueder, A. et al. The pathogenic exon 1 HTT protein is produced by incomplete splicing in Huntington’s disease patients. Wellington, C. L. et al. Caspase cleavage of mutant Huntingtin precedes neurodegeneration in Huntington’s disease. ...
Gene replacement using adeno-associated virus (AAV) vectors is a promising therapeutic approach for many diseases1,2. However, this therapeutic modality is challenged by the packaging capacity of AAVs (approximately 4.7 kilobases)3, limiting its appli