Medical imaging related knowledge and skills are widely used in clinical practice. However, radiology teaching methods and resultant knowledge among medical students and junior doctors is variable. A systematic review and meta-analysis was performed to compare the impact of different components of radiolo...
Antimicrobial resistance (AMR) causes high levels of global mortality. There is a global need to develop new antimicrobials to replace those whose efficacy is being eroded, but limited incentive for companies to engage in R&D, and a limited pipeline
as imaging is frequently utilised in medical practice. However, radiology is often under-represented in medical curricula [1,2]. Exposure to radiology education in medical school could result in better understanding of the role of imaging, leading to benefits such as enhanced selection of imaging, ...
Uveal melanoma (UM) is a rare ocular tumor. The loss of BRCA1-associated protein 1 (BAP1) and the aberrant activation of G protein subunit alpha q (GNAQ)/G protein subunit alpha 11 (GNA11) contribute to the frequent metastasis of UM. Thus far, limited mo
We understand plan quality in radiotherapy as the clinical suitability of the delivered dose distribution that can be realistically expected from a treatment plan. Plan quality is commonly assessed by evaluating the dose distribution calculated by the treatment planning system (TPS). Evaluating the 3D ...
In the preparatory phase, images of the patient are acquired. On these scans the clinical target area is delineated to which the radiotherapy dose is prescribed. In the 90s this area was delineated on conventional planar 2D X-rays, on which the target area (the prostate and seminal vesicles)...
The impact of molecular pathology in these tumors is multifaceted and bears diagnostic, prognostic, and predictive implications although its use in the clinical practice is not completely assessed. Genomic profiling data claim that genetic alterations in poorly differentiated and anaplastic thyroid carcinoma...
in a relational ciliopathy protein complex, a dynamic molecular machine that allows ciliary growth and function [13,15]. In addition, there is ample evidence to conclude that proteins in the ciliopathy network form sub-clusters, which are often associated with distinctive clinical characteristics ...
As life expectancy increases in many countries, the prevalence of age-related diseases also rises. Among these conditions, chronic kidney disease is predicted to become the second cause of death in some countries before the end of the century. An important problem with kidney diseases is the lack...
Clinically, FMT is defined as the administration of fecal matter solution from a healthy donor into the intestinal tract of a recipient [6,7]. The use of FMT in clinical trials has most commonly been to treat Clostridium difficile infections and irritable bowel disease, however case reports ...