When running a randomized controlled trial (RCT), a clinical site may face a situation when an eligible trial participant is to be randomized to the treatment that is not available at the site. In this case, there are two options: not to enroll the parti
doi:10.1080/01459740.2016.1160089InformaworldMedical Anthropology
Phase 1 is the initial introduction of an experimental drug or therapy to humans. This phase is the first step in the clinical research process involved in testing new or experimental drugs. The main goal of phase 1 studies is to establish the new drug’sside effects, as well as its metab...
Jon Kabat-Zinn is especially well-known for linking mindfulness to reducing stress and anxiety as the head of the Center for Mindfulness in Medicine, Health Care, and Society at the University of Massachusetts Medical School. Through the center, people from all walks of life, with a wide array...
RCT = Randomized clinical trial. From [4]. Levels of evidence is closely related to our current concepts on “Evidence Based Medicine (EBM)”. Sackett in 1997 wrote EMB “…whose philosophical origins extend back to mid-19th century Paris and earlier, is the conscientious, explicit and judicio...
Long covid (post covid-19 condition) is a complex condition with diverse manifestations, uncertain prognosis and wide variation in current approaches to management. There have been calls for formal quality standards to reduce a so-called “postcode lotte
Having a home is the foundation of most people’s lives. People with co-occurring substance use and mental health problems may experience challenges in acquiring and keeping housing. Many also have major health challenges. Supported housing is the subjec
A subsequent, randomized controlled trial (RCT) [8] comparing intravesical instillations of either a phage or a placebo versus standard-of-care (SOC) antibiotic treatment showed that intravesical phage therapy was non-inferior to the SOC, but not superior to placebo bladder irrigation in terms of...
Medical imaging related knowledge and skills are widely used in clinical practice. However, radiology teaching methods and resultant knowledge among medical students and junior doctors is variable. A systematic review and meta-analysis was performed to c
These interventions can include drugs, therapeutic agents, prophylactic agents, diagnostic agents, medical devices, procedures, vaccines and noninvasive approaches, such as modifying diet and exercise. One example of an interventional study is a randomized control trial (RCT). During a randomized control...