renal medicinesirolimusAutosomal dominant polycystic kidney disease (ADPKD) is the most common inherited renal disease, and sirolimus, a mammalian target of rapamycin (mTOR) inhibitor, has been shown to significantly retard cyst expansion in animal models. The optimal therapeutic dose of sirolimus is ...
Polycystic kidney disease is a genetic disorder that causes fluid-filled cysts to grow in the kidneys. At the same time, hydronephrosis is a condition that causes one or both kidneys to become stretched and swollen due to the build-up of urine inside them. Thus, this is the key diffe...
What renal disease is diabetic nephropathy associated with? What autoimmune diseases affect the kidneys? What is the etiology of polycystic kidney disease? What is the differential diagnosis associated with glucose in the urine? What are the consequences of ketone bodies?
What is the pathophysiology of renal failure? What is the pathophysiology of chronic kidney disease? What is the pathogenesis of kidney disease? What renal disease is diabetic nephropathy associated with? What is the etiology of polycystic kidney disease? What is autosomal polycystic kidney disease?
Chronic kidney disease is caused by underlying conditions like diabetes, high blood pressure, glomerulonephritis, interstitial nephritis, an inflammation of the kidney’s tubules and surrounding structures, polycystic kidney disease, prolonged obstruction of the urinary tract, vesicoureteral reflux and...
Causes Jack has a history of diabetes, which, along with high blood pressure, is the most common cause of ESRD. Glomerulonephritis, the inflammation of the glomeruli or other blood vessels in the kidneys, is another leading cause of this condition. Any kidney disease, including polycystic kidney...
Letrozole (Femara®) is a nonsteroidal, third-generation aromatase inhibitor administered orally once daily, which has shown efficacy in the treatment of postmenopausal women with early-stage or advanced, hormone-sensitive breast cancer.[1] Letrozole binds competitively to the heme of cytochrome P450...
Kidney indicates that something is affecting the kidneys. Possible causes of kidney pain include, but are not limited to, the following: Atheroembolic renal disease Bladder or ureter problems Cyst Hemorrhaging Hydronephrosis (blockage) Injury or trauma Kidney stones Mass or cancer Polycystic kidney dise...
“Impact of liver volume on polycystic liver disease-related symptoms and quality of life.” United European gastroenterology journal 6.1 (2018): 81-88. da Silva Dias, George Alberto, et al. “Correlation between clinical symptoms and peripheral immune response in HAM/TSP.” Microbial pathogenesis...
M. et al. The m-TOR pathway is regulated by polycystin-1 and its inhibition reverses renal cystogenesis in polycystic kidney disease. Proc. Natl Acad. Sci. USA 103, 5466–5471 (2006). Article CAS Google Scholar Qian, Q. et al. Sirolimus reduces polycystic liver volume in ADPKD ...