Polycystic kidney disease (PKD) is a monogenic, hereditary disorder of the kidneys that leads to fluid-filled cysts within the renal tubes. It is one of the most common causes of end-stage renal failure. There are two types, the more common autosomal dominant (ADPKD) and the rarer ...
Genitourinary systemPolycystic kidney disease·Medullary cystic kidney disease·Congenital cystic dysplasia Other conditionsHydatid cyst·Von Hippel-Lindau syndrome·Tuberous sclerosis Category:Channelopathy This article is licensed under theGNU Free Documentation License. It uses material from theWikipedia article...
7, Claudia Izzi7, Alberto Edefonti8, Susanna Negrisolo9, Elisa Benetti10, Maria Teresa Sciarrone Alibrandi11, Paolo Manunta11, Alessandra Boletta3 & Maurizio Ferrari1,2,12 Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common hereditary kidney disease. ...
Autosomal recessive polycystic kidney disease (ARPKD) is very rare and affects 1 in 20,000 - 40,000 live births.[1]ARPKD has a much more severe clinical course and is caused by mutations in polycystic kidney and hepatic disease 1 (PKHD1), which encodes fibrocystin.[1]ARPKD usually present...
International Journal of Nephrology and Renovascular Disease Dovepress open access to scientific and medical research Open Access Full Text Article Polycystic kidney disease: inheritance, pathophysiology, prognosis, and treatment REVIEW Christian R Halvorson1 Matthew S Bremmer1 Stephen C Jacobs1 1Department...
This chapter provides significant information on polycystic kidney disease (PKD) that describes a heterogeneous set of disorders resulting from single gene defects transmitted as either autosomal dominant or autosomal recessive traits. One of these disorders, autosomal dominant polycystic kidney disease (...
ArticleOpen access02 September 2022 Culture and analysis of kidney tubuloids and perfused tubuloid cells-on-a-chip 05 March 2021 Introduction Autosomal dominant polycystic kidney disease (PKD) is commonly inherited as a heterozygous, loss-of-function mutation in eitherPKD1orPKD2, which encode the pr...
Hi. Polycystic kidney disease is one of the most common inherited disease that affects the kidneys. Children of parents with PKD have a 50% chance of getting the disease. But, PKD can be diagnosed in unborn babies – there is a test called amniocentesis. Also, there is another test, chori...
Autosomal Dominant Polycystic Kidney Disease — NEJM Review Article from The New England Journal of Medicine — Autosomal Dominant Polycystic Kidney Disease PA Gabow 被引量: 181发表: 1993年 Autosomal Dominant Polycystic Kidney Disease — NEJM Clinical Practice from The New England Journal of Medicine ...
Article Open access 27 July 2021 Glis2 is an early effector of polycystin signaling and a target for therapy in polycystic kidney disease Article Open access 01 May 2024 References Torres, V., Harris, P. & Pirson, Y. Autosomal dominant polycystic kidney disease. Lancet 369, 1287–1301 ...