0:09 | In terms of emerging trends and developments in the field of thyroid cancer research, there is a lot going on. It really is an exciting time. We have talked about precision medicine, and we are going to continue to make progress in precision medicine [and] targeted therapy for pa...
Until recently, most immunotherapeutic approaches used to fight cancer were ineffective, counteracted by the tumour’s ability to evade immune attack. However, extensive research has improved our understanding of tumour immunology and enabled the develop
As orphan drugs are considered an exception in class 1 (i.e. drug with an added value), a budgetary impact study is required in the reimbursement dossier but a cost-effectiveness analysis is not. The DRC is composed of one (non-voting) chairman and 30 members; 22 voting members (i.e....
Platinum-based chemotherapy is standard treatment for non-small cell lung cancer (NSCLC), but in the expanding world of tyrosine kinase inhibitors established regimes are being questioned. Ramalingham et al (J Clin Oncol 2015;33:433–41) have published a Phase II randomised, double-blind, place...
Transcript:Maciej Mrugala, MD, PhD, MPH: Glioblastoma is a primary brain tumor that originates, typically, in the brain structures. It is in that way different from other primary solid tumors, let’s say breast cancer or melanoma, that can potentially travel to the brain. This means that ...
As orphan drugs are considered an exception in class 1 (i.e. drug with an added value), a budgetary impact study is required in the reimbursement dossier but a cost-effectiveness analysis is not. The DRC is composed of one (non-voting) chairman and 30 members; 22 voting members (i.e....
The method has been successfully used in characterisation and detection of brain and prostate cancer and there is some evidence towards its use as a response biomarker following chemotherapy in breast cancer (Baek et al, 2009). There is yet not enough evidence to support the role of MRS as a...
In 80% of cases, HCC arises in patients with cirrhosis with previous hepatitis B and C infection or alcoholics and it is the most widespread primary liver cancer [1,2]. In cirrhotic liver, HCC shows hyperenhancement of the arterial phase, followed by a delayed portal or venous phase ...
3. Role of Angiogenesis in NETs 3.1. Rationale for Targeting Angiogenesis Angiogenesis is one of the hallmarks of cancer as it plays a key role in providing oxygen and nutrients for tumor cell growth and progression [79]. Targeting angiogenesis has been successfully explored as a therapeutic str...
metastatic castration-sensitive prostate cancer; NR: not reported; NYR: not yet reached; OS: overall survival; PCa: prostate cancer; PFS: progression-free survival; PSA: prostate-specific antigen; rPFS, radiographic progression-free survival; RP: radical prostatectomy; RT: radiation therapy; SOC: ...