Recent years have seen so-called natural killer T (NKT) cells emerge as important regulators of the immune response. The existence of NKT-cell subsets, and other types of T cell that resemble NKT cells, is an ongoing source of confusion in the literature. This perspective article seeks to ...
Recent years have seen so-called natural killer T (NKT) cells emerge as important regulators of the immune response. The existence of NKT-cell subsets, and other types of T cell that resemble NKT cells, is an ongoing source of confusion in the literature. This perspective article seeks to ...
Godfrey DI,MacDonald HR,Kronenberg M,et al.NKT cells: what’s in a name[].Nature Reviews Immunology.2004Godfrey DI;MacDonald HR;Kronenberg M.NKT cells:what's in a name,2004Godfrey DI, MacDonald HR, Kronenberg M, Smyth MJ, Van Kaer L (2004) NKT cells: What's in a name? Nat Rev...
Altered cellular SM homeostasis disrupts the development and function of natural killer T cells by obstructing the presentation of lipid agonists by CD1d molecules.doi:10.1038/s41590-019-0525-8Sebastian JoyceBenjamin W. SpillerLuc Van KaerNature Immunology...
Natural killer T (NKT) cells are a unique population of lymphocytes that coexpress a semiinvariant T cell and natural killer cell receptors, which are part... G Gonzalez-Aseguinolaza,Camila de OIiveira,M Tomaska - 《Proceedings of the National Academy of Sciences of the United States of ...
Godfrey DI, MacDonald HR, Kronenberg M, Smyth MJ, Van Kaer L: NKT cells: what's in a name? Nat Rev Immunol 2004;4:231-237. 36. Olszak T, An D, Zeissig S, Vera MP, Richter J, Franke A, Glickman JN, Siebert R, Baron RM, Kasper DL, Blumberg RS: Microbial exposure during ea...
NK cells and NKT cells. In the in vitro study, PBMCs were treated with IMiDs (thalidomide, lenalidomide and pomalidomide) for 7 days, and Foxp3+CTLA-4highCD25highCD4+cells were detected. The results showed that the proportion of Tregs in thalidomide group did not change significantly, whil...
NKT cells, which have been a part of research into cancer and other diseases, have not previously been the focus of HIV research, Lang said. The research will last 18 months, with tests being performed on mice.The Oklahoma Center is giving ＄300,000 toward the research, and if the resear...
NKT cells are able to produce both T helper (Th) 1 and Th2 cytokines but their depletion in NAFLD has been associated with Th1 polarization of hepatic T cells in mice[44,45]. Two T helper cell subsets were recently discovered and are strictly related to the innate immune response. Th17 ...
[40]. Therefore, these cells seem to be involved in the pathogenesis of IBD and CAC, but their exact role is not yet clear and requires further study. Another group of immune cells that appear to be involved in the pathogenesis of IBD are NKT cells. The development of these cells ...