Recent years have seen so-called natural killer T (NKT) cells emerge as important regulators of the immune response. The existence of NKT-cell subsets, and other types of T cell that resemble NKT cells, is an ongoing source of confusion in the literature. This perspective article seeks to ...
Recent years have seen so-called natural killer T (NKT) cells emerge as important regulators of the immune response. The existence of NKT-cell subsets, and other types of T cell that resemble NKT cells, is an ongoing source of confusion in the literature. This perspective article seeks to ...
Recent years have seen so-called natural killer T (NKT) cells emerge as important regulators of the immune response. The existence of NKT-cell subsets, and other types of T cell that resemble NKT cells, is an ongoing source of confusion in the literature. This perspective article seeks to ...
It plays an immunomodulatory role while killing tumor cells, and enhances the activity of CD8+ T cells, NK cells and NKT cells. In the in vitro study, PBMCs were treated with IMiDs (thalidomide, lenalidomide and pomalidomide) for 7 days, and Foxp3+CTLA-4highCD25highCD4+ cells were ...
It plays an immunomodulatory role while killing tumor cells, and enhances the activity of CD8+ T cells, NK cells and NKT cells. In the in vitro study, PBMCs were treated with IMiDs (thalidomide, lenalidomide and pomalidomide) for 7 days, and Foxp3+CTLA-4highCD25highCD4+ cells were ...
Increased tumor infiltration of NKT cells is associated in CRC with a better prognosis[16]. Human γδ T cells (γδ T cells) express a receptor to antigens combining a γ chain and a δ chain. This receptor can recognize different antigens usually in a non-MHC-restricted way, such as...
NKT cells are able to produce both T helper (Th) 1 and Th2 cytokines but their depletion in NAFLD has been associated with Th1 polarization of hepatic T cells in mice[44,45]. Two T helper cell subsets were recently discovered and are strictly related to the innate immune response. Th17 ...
[40]. Therefore, these cells seem to be involved in the pathogenesis of IBD and CAC, but their exact role is not yet clear and requires further study. Another group of immune cells that appear to be involved in the pathogenesis of IBD are NKT cells. The development of these cells ...
E. et al. Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney. J. Biol. Chem. 272, 6471–6478 (1997). CAS PubMed Google Scholar Smith, H. W., Finkelstein, N., Aliminosa, L....
Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation. J. Exp. Med. 203, 2639–2648 (2006). CAS PubMed PubMed Central Google Scholar Day, Y. J. et al. A2A adenosine receptors on bone marrow-derived cells protect liver ...