Recent years have seen so-called natural killer T (NKT) cells emerge as important regulators of the immune response. The existence of NKT-cell subsets, and other types of T cell that resemble NKT cells, is an ongoing source of confusion in the literature
However, cell therapy isn’t without its practical challenges. By educating ourselves on how cell therapy works, and identifying potential solutions to its obstacles, we can all work towards empowering cell therapy technology to meet its potential. What is Cell Therapy? Cell therapy is the process...
CELLULAR therapyBONE marrowPeripheral T cell lymphoma (PTCL) is a rare and aggressive type of non-Hodgkin's lymphoma that affects mature T cells. This type of cancer is characterized by the abnormal growth of T cells, which can accumulate in the lymph nodes, spleen,...
They are fully activated to carry out their immune functions, and most will die once this function is no longer needed. What Cell Populations Are Used in Cell Therapy? Numerous immune cells including T cells, B cells, and NK cells are the most common starting material in adoptive cell ...
Therapy:Isolates immune cells from the patient to expand a specific cell population or modify them to recognize a cancer antigen. Adoptive cell therapies include CAR-T therapy, tumor-infiltrating lymphocytes (TIL) therapy, engineered T-cell receptor therapy, and natural killer (NK) cell therapy. ...
Regional Expression of CXCL12/CXCR4 in Liver and Hepatocellular Carcinoma and Cell-cycle Variation during in vitro Differentiation The CXCL12/CXCR4 system may be important in carcinoma. Expression of the a-chemokine SDF-l伪 (stromal cell derived factor-l伪)/CXCL12 mRNA is reduced in ma......
"This is really exciting on two levels: on a fundamental level, our findings show that a cell's function can be directly linked to its nutrition; on a more specific level, this sheds new light on how T cells become dysfunctional or exhausted and what we could do to prevent that." ...
Advancement of CAR T-cell constructs and newer immunotherapies such as NK cell therapy, tumor-infiltrating lymphocytes, and T-cell receptor-engineered T-cell (TCR-T) therapy hold promise for avoiding the toxicities associated with CAR T-cell therapy but will likely come with their own novel set...
Studies of ex Vivo Activated and Expanded CD8 + NK-T Cells in Humans and Mice immunotherapyAdoptive cellular therapy holds promise for improving the outcome of hematopoietic cell transplantation (HCT). At present, donor lymphocyte infusion... MR Verneris,J Baker,M Edinger,... - 《Journal of ...
What are the effects of drugs on Treg cells in multiple myeloma, and what are the applications of treg cells in therapy? Introduction Multiple myeloma (MM) is the most common form of plasma cell malignancy, accounting for about 1.7% of all malignant tumors [1]. Although the use of a vari...