et al. Dietary intervention impact on gut microbial gene richness. Nature 500, 585–588 (2013). Article CAS PubMed Google Scholar Hildebrandt, M. A. et al. High-fat diet determines the composition of the murine gut microbiome independently of obesity. Gastroenterology 137, 1716–1724 (2009)...
However, due to the lack of MMR genes in tumor cells or defects in the process of replication repair, the possibility of gene mutation is increased [2]. It can be seen that MSI is an important factor in the occurrence and development of tumors. In line with the frequency of MSI, it ...
Gene transposition is the process by which a transposon DNA "jumps" from one chromosomal locus to another. In this process,there is the participation of transposase. Single-cell DNA sequencing takes advantage of this feature by pre-assembling the barcode DNA with the transposase Tn5 and encapsulati...
Nevertheless, evidence is accumulat... A Velando,R Torres,C Alonso-Alvarez - 《Bioessays》 被引量: 151发表: 2008年 Debunking the slippery slope argument against human germ-line gene therapy. This paper attempts to debunk the slippery-slope argument against human germ-line gene therapy by ...
adenomatous polyposis: apc Familial non-polyposis colon cancer: MSH2 Li-Fraumeni syndrome: p35 Multiple endocrine neoplasia: RET Common diseases: [gene related] Schizophrenia: B5 Rheumatoid arthritis ( *** ): DR4 Rheumatoid arthritis (juvenile ): B27 Multiple sclerosis: DR7 and DR2 ...
’; (iv) anxiety and drastic lifelong fear of cancer if the patient is found to harbor a cancer-associated mutation; (v) individuals not wanting to know molecular genetic test results (∼20% of our patients who have been tested decline to receive this information about their gene status.)...
miRNA Function Putative targets Reference miR-17-92 Down-regulated in IRF9, RAB10, [72] imatinib treated TXNIP, TET2 CML cells miR-21 Antisense TXPAN2, LUM, [73] inhibition leads SUZ12, MSH2, to inhibition of PDZD2 migration and cell growth and induces apoptosis miR-203 Methylated in ...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook AcronymDefinition NSGCNational Society of Genetic Counselors NSGCNova Scotia Geomatics Centre(Canada) NSGCNaval Security Group Command(US Navy) NSGCNational Space Grant Consortia ...
Design: We tested 88 adenomas from 49 proven mutation carriers (23 female and 26 male) from 37 Lynch syndrome families (12 MLH1, 21 MSH2, 3 MSH6 and 1 PMS2) enrolled in the Australasian Colorectal Cancer Family Study which is part of the Colon Collaborative Family Registry (C-CFR). The...
• Fode M, Hatzichristodoulou G, Serefoglu EC, Verze P, Albersen M, Group YAUMsH. Low-intensity shockwave therapy for erectile dysfunction: is the evidence strong enough? Nat Rev Urol. 2017;14(10):593–606. https://doi.org/10.1038/nrurol.2017.119. Review of Li-ESWT. Article PubMed...