Alcohol-related fatty liver disease, or simple steatosis, is the mildest stage of ALD. The terms steatosis and fatty liver both refer to the accumulation of fat in the liver. At this stage, the injury to the liver is minimal. Alcohol-related hepatitis(AH) is a more severe form of ALD....
Fat accumulation in the liver in the absence of specific causes of hepatic steatosis, such as alcohol consumption, with or without liver inflammation and its consequences, is described as non-alcoholic fatty liver disease (NAFLD)[1]. To date, there are no studies that highlight the link betwee...
hepatic steatosisnon-alcoholic fatty liver diseaseobesitywaist-to-height ratioBackground:The aim of this study is to identify obese children who are candidates for a potential diagnosis of non-alcoholic fatty liver disease (NAFLD).Methods:We enrolled 242 obese children (122 boys and 120 girls) age...
The gain in sensitivity allowed the detection of persons with minimal to mild histologic lesions, primarily patients with fatty livers (hepatic steatosis). Hepatic steatosis was diagnosed on the basis of hyperechoic ultrasonographic patterns of the liver because the mildness of laboratory abnormalities ...
Enhancing liver mitochondrial fatty acid oxidation capacity in obese mice improves insulin sensitivity independently of hepatic steatosis. Journal of Hepatology 56: 632–639. doi:10.1016/j.jhep.2011.10.008. Article PubMed CAS Google Scholar Montell, E., M. Turini, M. Marotta, M. Roberts, V....
For example, the type of protein may modulate weight high fat (20–40%) to induce metabolic perturbations, such as gain in rodents—rats fed soy diets have less hepatic lipid increased body weight, abdominal fat deposition, hyperleptine- mia, hyperinsulinemia, and hyperglycemia.15–17 High-...
However, while such strategies that target the gut microbiota to influence brain health and function are currently under development with varying levels of success, still very little is yet known about the triggers and mechanisms underlying the gut microbiota’s apparent influence on cognitive or ...
5,6 In general, T2DM is induced in experimental animals by surgical, chemical, dietary and genetic manipulations as well as combinations thereof. The most common obese models of T2DM are of spontaneous genetic origin (for example, naturally occurring mutations in leptin and leptin receptor)7 or ...
In the treatment of diabetes, Ong et al. [62] observed that Chlorogenic acid inhibited glucose-6-phosphatase (G-6-P) in the liver of Leprdb/db diabetic mice. ) expression and activity, reduce hepatic steatosis, improve lipid distribution and skeletal muscle glucose uptake, thereby improving fas...
itsabilitytocauseinsidiousand progressive liver damage in the majority of patients. 85% of HCV-infected patients will become chronically infected, usually for decades, leading to hepatic fibrosis, cirrhosis, and ultimately hepatocellular carcinoma El-Zayadi et al., 1997. How hepatitis ...