Chronic hepatitis with hepatic fibrosis or cirrhosis Alcohol-related fatty liver disease, or simple steatosis, is the mildest stage of ALD. The terms steatosis and fatty liver both refer to the accumulation of fat in the liver. At this stage, the injury to the liver is minimal. Alcohol-relat...
The gain in sensitivity allowed the detection of persons with minimal to mild histologic lesions, primarily patients with fatty livers (hepatic steatosis). Hepatic steatosis was diagnosed on the basis of hyperechoic ultrasonographic patterns of the liver because the mildness of laboratory abnormalities ...
In IBS subjects a low chronic inflammation is present and many other immune phenomena are also points of contact with hepatic steatosis. The intestinal mucosa physiologically contains immune cells much more than other organs and tissues, and this is mainly due to its anatomical configuration and func...
biochemical parameter model.Conclusions:A diagnostic approach to hepatic steatosis is recommended as part of the proper screening and stratification of risk factors in obese children.WHtR is a simple and convenient method of effectively identifying obese children who are candidates for hepatic steatosis ...
Enhancing liver mitochondrial fatty acid oxidation capacity in obese mice improves insulin sensitivity independently of hepatic steatosis. Journal of Hepatology 56: 632–639. doi:10.1016/j.jhep.2011.10.008. Article PubMed CAS Google Scholar Montell, E., M. Turini, M. Marotta, M. Roberts, V....
In the treatment of metabolic syndrome, Ma et al. [71] studied to evaluate the role of Chlorogenic acid in metabolic syndrome and found that the prevention and treatment of Chlorogenic acid has an effect on obesity and obesity-related mice. Hepatic steatosis and insulin resistance have good effe...
From high-fat-fed rodents to human obesity M Lai et al as has been shown for low-density lipoprotein receptor knockout mice on a C57BL/6J background who lost their lard-based HFD- induced mild hyperglycemia after 40 weeks.48 This is rather unexpected as C57BL/6J is reported to develop ...
Consequently, attention is now turning to how the microbiota can become the target of nutritional and therapeutic strategies for improved brain health and well-being. However, while such strategies that target the gut microbiota to influence brain health and function are currently under development ...
The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse. Cell Metab 2005; 1: 245–258. CAS PubMed Google Scholar Lan H, Hoos LM, Liu L, Tetzloff G, Hu W, Abbondanzo SJ et al. Lack of FFAR1/GPR40 does not protect mice from high...
In the absence of adiponectin, FGF21 can still reduce body weight but is no longer capable of improving glucose homeostasis, insulin resistance, hypertriglyceridemia, or hepatic steatosis (Holland et al., 2013, Lin et al., 2013). Finally, thiazolidinedione (TZD) agonists of PPARγ used ...