Dasatinib, at nanomolar concentrations, inhibits the following kinases: BCR-ABL, SRC family (SRC, LCK, YES, FYN), c-KIT, EPHA2, and PDGFRβ. Based on modeling studies, dasatinib is predicted to bind to multiple conformations of the ABL kinase. In vitro, dasatinib was active in leukemic ce...
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CaMLCKCalmodulin Myosin Light Chain Kinase(also seen as Cal-MLCK) Copyright 1988-2018AcronymFinder.com, All rights reserved. Suggest new definition Want to thank TFD for its existence?Tell a friend about us, add a link to this page, or visitthe webmaster's page for free fun content. ...
In the second part of this chapter, we therefore delineate how diffusion models can be implemented for data analysis. As a showcase, we discuss recent single molecule data obtained on Lck, an important kinase in T cell signaling.doi:10.1007/4243_2011_38Mario Brameshuber...
Looking for online definition of CAMLC or what CAMLC stands for? CAMLC is listed in the World's most authoritative dictionary of abbreviations and acronyms
kinase phosphorylation Expression Brain, smooth muscle, skin, gastrointestinal and genitourinary tract, adrenal medulla, immune system and heart Brain, smooth muscle, skin, gastrointestinal and genitourinary tract, adrenal medulla, immune system and heart Widely found in brain and gastric mucosa ...
Antigen binding to the TCR results in the intracellular phosphorylation (by a member of the Src kinase family called Lck) of a motif on the cytosolic tail of the TCR/CD3 complex, called the immunoreceptor based activation motif (ITAMs). ...
The perception of bronchial asthma has fundamentally changed during the last decade. Consequently, the Global Initiative for Asthma (GINA) suggested a new definition of asthma: “Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation. It is defined by the history of ...
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T-Lymphocyte Colony Forming Cell T-Lymphocyte Colony-Enhancing Factor T-Lymphocyte Polyclonal Proliferation T-lymphocyte specific protein tyrosine kinase p56lck T-lymphocyte subsets T-lymphocyte subsets T-lymphocyte subsets T-Lymphocyte-Derived Macrophage Chemotactic Factor ▼...