Myc-induced SUN domain-containing protein (Misu or NSun2) is a nucleolar RNA methyltransferase important for c-Myc-induced proliferation in skin, but the m... S Hussain,SB Benavente,E Nascimento,... - 《Journal of Cell Biology》 被引量: 145发表: 2009年 Phosphorylation of NuSAP by Cdk1...
Estrogen is the major female sex steroid and its main site of production is the granulosa cells in the ovarian follicle. In the serum, almost all of estrogen is bound, mainly to sex hormone binding globulin (SHBG) and albumin. The average concentration of estrogen in the follicular fluid is...
Research in this area has the potential to inform our understanding of the developmental origins of gender identity and sex difference in response to gonadal steroid manipulations, but care is needed in our research questions and methods to not further stigmatize sex and gender minorities. This is ...
The Barents–Kara region is significantly affected by climate change, leading to the rapid degradation of habitats and the infiltration of new potential infectious agents dangerous to pagophilic species, particularly the polar bear (Ursus maritimus). For individuals captured in the Barents Sea and the...
This lack of basic information on taxonomic diversity has significant implications for many aspects of evolutionary biology. While the figure of 1.5 million estimated fungal species is commonly used, critics have questioned the validity of this estimate. Data on biogeographic distributions, levels of ...
KD Queiroz - 《Systematic Biology》 被引量: 3238发表: 2007年 Size and shape in ontogeny and phylogeny We present a quantitative method for describing how heterochronic changes in ontogeny relate to phyletic trends. This is a step towards creating a unified ... P Alberch,SJ Gould,GF Oster,....
They use feedback to change both their cognitive and behavioural learning strategies, but how they choose which feedback to implement is complex. They struggle to generate learning strategies and expect teachers to make sense of the “how” in addition to the “what”” in planning future ...
Irritable bowel syndrome (IBS) is one of the functional psychosomatic gastrointestinal disorders (FGIDs) that, despite differences in location and symptom patterns, share common features with regard to their motor and sensory physiology, central nervous system (CNS) relationships, and the approach to ...
The prospect of transgenic marmoset models of human disease, readily available in the way that transgenic laboratory mice are currently, prompts excitement in the scientific community; but the idea of monkeys being bred to carry diseases is also contentious. We structure an ethical analysis of the ...
Using cryo-electron microscopy, it becomes possible to view cells, cell organelles as well as macromolecules complexes of well over 500 kD. Recently, Cryo-Electron Microscopy was also used to determine high resolution structures of 200kD proteins, which was a great achievement in the world of ...