Intravascular large B-cell lymphoma (IVLBL), which is a well-recognized entity, has two distinct patterns of presentation: the Western variant, mainly affecting skin and CNS, and the Asian variant, usually involving multiple organs and often associated to hemophagocytic lymphohistiocytosis (HLH) and...
Vitamin D might play a role in counteracting COVID-19, albeit strong evidence is still lacking in the literature. The present multicenter real-practice study aimed to evaluate the differences of 25(OH)D3 serum levels in adults tested for SARS-CoV-2 (acut
(HLH) is particularly harmful because it is characterized by the massive production and release of inflammatory mediators caused by the uncontrolled activation of T-lymphocytes, NK-cells, and macrophages; the ensuing clinical picture resembles septic shock and can determine a multiple organ dysfunction ...
MAS is a rare, life-threatening condition characterised by uncontrolled hyperinflammation which may develop on a background of rheumatic diseases such as sJIA. It is classified as a secondary form of HLH and is caused by excessive activation and expansion of T cells and macrophages. Biovitrum AB ...