HR stands for hormone receptor, and HER2 stands for human epidermal growth factor receptor 2. Learn about the difference between these types of breast cancer.
Triple-negative (ER-negative, PR-negative, HER2/neu not overexpressed) breast cancer has distinct clinical and pathologic features, and is a clinical problem because of its relatively poor prognosis, aggressive behaviour and lack of targeted therapies, leaving chemotherapy as the mainstay of treatment...
Breast cancer is a disease that starts in the breast with a malignant tumor. A malignant tumor is a mass of cells that grows out of control. The cancerous cells can also metastasize, or move to other tissues or parts of the body. The cancer can develop in any of the three types of ...
937 Words 4 Pages Open Document Breast cancer is one of the most common cancers and the second leading cause of cancer-related death among women in the United States. Up to 6% of breast cancers are advanced or metastatic at the time of diagnosis, requiring chemotherapy1, 2. Aberrant, accele...
When hormone receptor expression and HER2 markers are negative, this is known as triple negative breast cancer. Metastatic triple negative breast cancer is often treated with a range of chemotherapy agents and immunotherapy. Metastatic breast cancer survival rate ...
Treatment of HER2-positive breast cancer The human epidermal growth factor receptor 2 gene (HER2) is overexpressed and/or amplified in 鈭 15% of breast cancer patients and was identified a quarter ... MC Figueroa-Magalhães,D Jelovac,RM Connolly,... - 《Breast》 被引量: 141发表: 2014年...
Passage 9What is IBRANCE?IBRANCE is a prescription medicine used to treat HR+and HER2-breastcancer that has spread to other parts of the body.Important Safety Information for PatientsBefore you take IBRANCE,tell your doctor if you:●have fever,chills,or any other signs or symptoms of infection...
Like PIK3CA, HER2 is not an inherited gene mutation. Most breast cancer is HER2-negative. Research suggests about only 10% to 20% of cases are HER2-positive. This means there’s a change in the HER2 gene that makes breast cells grow and divide out of control. If you have invasive breas...
Hormone therapytreats breast cancers that respond to estrogen and/or progesterone. It lowers the amount of estrogen in your body or blocks the effects of estrogen so that it can't help your cancer grow. Targeted therapyworks against breast cancers that use proteins such asHER2to help them grow...
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