Acute heart failure (AHF) is a major burden disease, with a complex physiopathology, unsatisfactory diagnosis, treatment and a very poor prognosis. In the last two decades, a number of drugs have progressed from preclinical to early and late clinical development, but only a few of them have ...
which would otherwise be compromised by smearing of the bright-blood lumen signal. Two-dimensional (2D) T2-weighted (T2w) spin-echo sequences have inherent blood suppression due to outflow effects at long echo times; however, this mechanism is not compatible with short echo times needed for ...
Understanding the diversity of life and how species have evolved into their different and specialized forms is an ultimate goal of evolutionary biology. The events that lead to macroevolutionary diversification by adaptive radiation have been related to ecological opportunities: the availability of new ec...