1.热镀纯锌镀层 hot-dip zinc coating(Z) 热镀锌生产线上,将经过预处理的钢带浸入熔融锌液中所得到的镀层。熔融锌液中锌含量应不小于 2.热镀锌铁合金镀层 hot-dip zinc-iron alloy coating(ZF) 热镀锌生产线上,将经过预处理的钢带浸入熔融锌液中所得到的镀层。熔融锌液中锌含量应不小于 随后,通过合金化...
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Unexpectedly, YAP governs the mechanoresponse of Imp7 by forming a YAP/Imp7 complex that responds to mechanical cues through the Hippo kinases MST1/2. Furthermore, YAP behaves as a dominant cargo of Imp7, restricting the Imp7 binding and the nuclear translocation of other Imp7 cargoes such ...
Ionotropic glutamate delta receptors 1 (GluD1) and 2 (GluD2) exhibit the molecular architecture of postsynaptic ionotropic glutamate receptors, but assemble into trans-synaptic adhesion complexes by binding to secreted cerebellins that in turn interact with presynaptic neurexins1,2,3,4. It is unclea...
Reliance Electric HR2000/BLA-16-1 Brushless AC Servo 3-Phase 200/220/230V Drive Reliance Electric 45C-400A/45C400A/45C400/45C-400 RELIANCE ELECTRIC V*S GP2000 20HP 460V AC DRIVE 2GU41020 RELIANCE ELECTRIC 284T MOTOR *** RELIANCE ELECTRIC 702805-12-AZ REMOTE OPERATION STATION *NEW NO ...
(D) NG108-15 cells were incubated (2 hr, 37°C) with PRE-084 (25 μM) or BD1047 (25 μM), and then, in the continuous presence of the Sig-1R ligands, loaded with Fluo-8 by incubation with Fluo-8 AM in HEPES-buffered saline (HBS) (30 min, 20°C, with a further 30 min...
While HR is the predominant repair pathway in yeast, NHEJ is mostly utilized in higher eukaryotes and represents the DNA repair pathway followed during V(D)J recombination. At least two protein complexes are thought to act in concert or sequentially at the site of the RAG1/2-derived dsb. ...
1. There is compelling evidence that PM has detrimental impacts on the respiratory and cardiovascular systems. For example, poor air quality is associated with an increased incidence of stroke and myocardial infarctions, an increase in emergency hospital admissions related to asthma, chronic obstructive...
We found that NCK-associated protein 1 (NCKAP1) was significantly increased in the blood RNA of patient-derived xenograft (PDX) models of colon cancer. In the NCKAP1 gene knockdown-induced human colon cancer cell lines HCT116 and HT29, there was a reduced wound healing area and significant...
6b). Interestingly, the highest efficacy was achieved with abemaciclib (IC50 467 nM), a Cdk4/Cdk6 inhibitor, which was approved by the FDA in 2017 for the treatment of hormone receptor positive (HR+) and HER2-negative metastatic breast cancer40,41,42. Also, GSK1059615 (IC50 1079 nM...