What is the Matrix? ECM Regulation of Cellular Behaviors, Angiogenesis, and CancerBerkeley Electronic Press Selected WorksAllan Albig
Traditional cell culture is done on a two-dimensional plane, which means that cells are interacting with each other in two dimensions. By adding a third dimension, usually by combining the cells in a biomaterial serving as the ECM of the cells, we allow cells to interact with each other in...
Accordingly, the TME is closely related to the diverse biological behaviors of tumors [1–3]. Cancer-associated fibroblasts (CAFs) are an impor- tant component of the tumor stroma. CAFs interact with tumor cells in various ways, such as by remodeling the ECM and secreting cytokines and ...
Partial wave spectroscopy takes advantage of the field effect to allow for the sensitive and specific detection of cancers in tissues that are difficult to reach. Cancer is an extraordinarily complex disease. Methods that are commonly used in physics can reduce the complexity of cancer to a ...
Understanding how cancerous cells spread from a primary tumor is important for any number of reasons, including determining the aggressiveness of the disease itself. The movement of cells into the extracellular matrix (ECM) of neighboring tissue is an essential step in cancer progression that directly...
including fatigue and a propensity for cancer relapse due to the release of SASP components. Therefore, a complete understanding of the mechanisms of senescence is required to exploit the balance between its beneficial and harmful effects to effectively treat pathological states and potential slow the ...
Leukemia is cancer of the blood and bone marrow that causes abnormal production of white blood cells, and this condition has different classifications depending on the location of the cancer. Learn about the different types of leukemia and the cells associated with cancer, and understand the differe...
ECM and MMP activity are also highly upregulated in RV infection with asthma. Created with BioRender.com Full size image Directly surrounding the airway epithelium is the sub-epithelial space, which contains mesenchymal-like cells including fibroblasts, myofibroblasts, and smooth muscle, as well as ...
Answer to: What is the main ground substance (or ECM) component that makes up cells? By signing up, you'll get thousands of step-by-step solutions...
in various organs. Fibrosis involves the abnormal deposition of fibrous extracellular matrix (ECM), leading to an increase in fibrous tissue and a decrease in the number of parenchymal cells in organs and tissues such as the lungs, heart, liver, and kidneys [16]. This pathology is ...