In lupus model mice, anti-nucleosome antibodies are reported to emerge even before the production of anti-dsDNA antibodies. BK virus T antigen, bacterial DNA, a DNA binding protein nucleobindin and autoreactive helper T cells specific to nucleosome or anti-DNA antibody-derived peptides have been...
该23岁女性患者具有6年难治性SLE病史,临床表现为活动性狼疮性肾炎、溶贫、多形性皮疹和多关节炎。经过双抗治疗,患者外周血B细胞迅速耗竭,抗dsDNA抗体转阴,且黏膜皮肤和肌肉骨骼症状实现了快速且不依赖药物的完全缓解,为难治性SLE患者开辟了新的治疗...
Other first-line tests for differential diagnosis include dsDNA, IgG; Smith/RNP, IgG; Smith (ENA), IgG; SSA 52 and 60, IgG; SSB, IgG; Jo-1, IgG; Scl-70, IgG. 16 (The Choosing Wisely Campaign recommends not ordering ANA subserologies if the ANA is not positive.) 17 Connective tiss...
T7 噬菌体是一种典型的短尾裂解性噬菌体,由内径为55nm的二十面体头部(直径约为60nm)和19nm的尾部(含6根尾丝)组成外壳蛋白,包裹一条长为40kbp的线性dsDNA基因组(含55个基因)。T7噬菌体的宿主菌为表面粗糙的大肠杆菌,前者通过尾丝蛋白识别吸附到后者的受体上,然后通...
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They are called nucleoids. Unlike eukaryotic nuclei, they are not enclosed in the nuclear membrane and lack nucleolus and nucleoplasm. It is represented by a dsDNA molecule either in a closed circular form or in coiled form. Bacterial DNAs are found either in nucleoid as chromosomal DNA or ou...
What is the significance of a positive test for HIV antibody? Describe the adaptive significance of an amniote egg. What is cDNA and why is it important? What are the basic features of a plasmid vector? Describe the purpose of the differential centrifugation. ...
porto-sinusoidal vascular disorder, PSVD, obliterative portal venopathy, non-cirrhotic portal hypertension, rheumatology, systemic autoimmune disease, systemic lupus erythematosus, antiphospholipid antibody, Sjogren's, systemic sclerosis, inflammatory myositis, vasculitis, rheumatoid arthritis, Felty's syndrome....
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Twitter Google Share on Facebook AcronymDefinition cANCACytoplasmic Antineutrophil Cytoplasmic Antibody(pathology) cANCACombined Aboriginal Nations of Central Australia cANCAClassic AntiNeutrophil Cytoplasmic Antibody cANCACirculating Anti-Neutrophil Cytoplasmic Antibody ...