What Should Be the Goals of Apolipoprotein A1? Analysis of a Healthy Population from Argentinadoi:10.1016/j.jacl.2012.04.007DanielAlbertoSiniawskiandWalterM.MassonandPatriciaSorrocheSDOSJournal of Clinical Lipidology
However, LDL is a com- by activated platelets may also induce the oxidativeSome interesting questions could be raised by our modifica- plex particle consisting of a lipid core surrounded by apolipoprotein tion of Apo B-100 in the absence of lipid peroxidation of LDL.Oxidized LDL: biomarker ...
Indeed, this scenario is illustrated by the INTERHEART study, a global case–control study which highlighted the relevance of both atherogenic apolipoprotein (apo) B100-containing lipoproteins and potentially atheroprotective apoA-I containing lipoproteins, such as high-density lipoproteins (HDL), to ...
and the presence of modified lipoproteins not routinely measured in clinical practice. Nitrated lipoproteins are produced by the nitration of the tyrosyl residues of apolipoproteins by myeloperoxidase. There is some evidence from the research conducted showing that nitrated lipoproteins may play a role ...
Inflammation, promoted by apolipoproteins and oxidized phospholipids in the artery wall, and oxidative stress are also essential in the vascular calcification process [53,54]. Furthermore, it has been estimated that conventional risk factors account for 40% of the variability of coronary calcification...
[2] Nonstandard abbreviations: LC-MS/MS, liquid chromatography-tandem mass spectrometry; MRM, multiple reaction monitoring; apoB, apolipoprotein B; apoA-I, apolipoprotein A-I; TFE, trifluoroethanol; SISCAPA, stable isotope standards and capture by anti-peptide antibodies. Simultaneous quantification of...
double-blind trial to test whether probiotics would be clinically beneficial in MCI patients. These investigators reported that 16 weeks of treatment withBifidobacterium breve A1resulted in an improvement in Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and the JMCIS tests in...
A major consequence of ‘in vitro regeneration’ is the downregulation of metabolic genes that are typically abundantly expressed in the liver, suggesting an adaptation to a ‘proliferative’ state (Fig.2a). For instance, CYP enzymes (Cyp3a11andCyp2e1), apolipoproteins (Apoa2andApoc3), serine ...