Cell senescence is a process that occurs due to telomere erosion or can be induced by various stresses. Senescent cells cease to divide but remain alive, metabolically active and able to secrete many molecules. They also show many hallmarks of senescence, such as enlarged size, increased granulari...
Cellular senescence is a state of stable cell cycle arrest under which cells remain metabolically active, but no longer divide and do not respond to growth-promoting stimuli. Senescence is triggered by a variety of cellular stressors. These include environmental factors like ionizing radiation or exp...
Cellular senescence is a process that results from a variety of stresses and leads to a state of irreversible growth arrest. Senescent cells accumulate during aging and have been implicated in promoting a variety of age-related diseases. Cellular senescence may play an important role in tumor suppr...
as well as organismal senescence, which looks at the aging of an entire organism as a whole. Cellular senescence can be very interesting, as it can be used to see why some cells age differently than others, and how aging impacts the ability of a cell to function. One general rule of ce...
Have you heard the term senescence but you don’t know what it is? Want to learn techniques to study it? Look no further. Read this blog post.
Mesenchymal stromal cell senescence in multiple myeloma: what came first?doi:10.1055/s-0042-1757527Ilic, JSchlierf, BRudert, MEbert, RTrivanovic, DHerrmann, MOsteologie
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As we grow older, aches and pains can become a chronic part of life. But experts say it doesn't have to—and solutions are on the way.
aCritically short telomeres fail to form proper protective end structures, which are sensed as DSBs and trigger a permanent cell-cycle arrest known as senescence 重要地形成适当的防护末端结构的短的telomeres出故障,感觉作为DSBs并且触发一次永久细胞周期拘捕以衰老著名[translate] ...
Senescence is acellular mechanismactivated in stressed or damaged cells to end cellular growth and reproduction. When cells enter senescence, they release chemical compounds that signal the immune system to destroy them.1 However, as we get older, our bodies become less adept at removing senescent ...