Chromatin is the complex of DNA and proteins that are packed within the nucleus of eukaryotic cells. The interaction of these DNA and proteins is critical for cellular functions such as signal transduction, gene transcription,chromosomesegregation, DNA replication and recombination, and epigenetic silenci...
These alkaloid carcinogens, especially NNN, are considered as a risk factor for oropharyngeal carcinoma [5]. In an analysis of 44 NPs by Mallock et al., [6] nicotine contents of the products ranged from 1.79 to 47.5 mg/pouch. TSNAs were also detected in more than half of the 44 NP ...
Childhood obesity is an epidemic. What can be done to address this issue? What disorders result? Childhood Obesity: As the years pass, we continue to see upward trends in childhood obesity. Factors contributing to this are likely the availability of fast foods, in...
Acute ischemic stroke (AIS) is a threatening stressor and an increasingly major cause of death and disability, accounting for the leading criminal of hospitalization for neurologic diseases [1].In the acute early stage, profound alterations of the autonomic, endocrine, metabolic, and immune systems ...
For depolarizing responses of C-type HCs, the key factor is the electrical feedback from L-type HCs, which provides not only the response of opposite polarity (to red light), but also the typical feedback delay. 展开 关键词: Horizontal cells Model Electrical feedback Non-linear membrane ...
We know that a predisposition to become overweight is found in our genes. Now, we’re starting to learn thatepigeneticsalso has a hand in determining whether a person will become fat or lean. New research is uncovering the possibility of an epigenetic switch that is, interestingly, either “...
What is the genetic inheritance of the Rh factor? Does it follow classical Mendelian genetics? Is it monogenic/polygenic? Explain. What is the difference between an autosomal dominant and autosomal recessive pattern of inheritance? Which of the following descriptions best fits the ...
Most of the identified genes involve transcription or epigenetic factors that influence the expression of other genes (some with an unknown function), consequently leading to a wide variety of symptoms that are shared among various neurodevelopmental disorders (Graham and Fisher, 2015). It is beyond...
Individuals of many animal species are said to have a personality. It has been shown that some individuals are bolder than other individuals of the same sp
Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis. EMBO J. 26, 4709–4719 (2007). CAS PubMed PubMed Central Google Scholar Kibe, T., Osawa, G. A., Keegan, C. E. & de Lange, T. Telomere protection by TPP1 is mediated by POT1a and ...