Epigenetics and Other Factors that Affect Folding and Stability of DNA I-Motif StructuresNot Availabledoi:10.1016/j.bpj.2014.11.2174Reilly, Samantha M.Bhavsar-Jog, Yogini P.Wingate, Sara E.Lyons, Daniel F.Wright, Robert T.Brooks, Tracy A....
Haematopoietic stem cells (HSCs) give rise to all cellular components of the immune system (lymphoid and myeloid). Although the haematopoietic compartment of bone marrow decreases with age, age does not appreciably affect the number and proliferative capacity of HSCs. However, through the normal matu...
establishing new cohorts is of interest to the field, to facilitate independent replication and increase sample sizes. When setting up these cohorts, extensive phenotypic data should be collected and included as covariates in analyses. Covariates that are known to affect epigenetic marks should be coll...
Epigenetics refers to a heritable alterations in gene function that happe... Charlotte Ling, Leif Groop - 《Diabetes》 被引量: 1436发表: 2009年 Putative environmental factors in Type 1 diabetes The article offers insights on epigenetic mechanisms linked with type 2 diabetes. Epigenetics refers to ...
It is now commonly accepted that white adipocytes actively secrete a wide range of bioactive molecules including leptin, adiponectin, resistin and many other signals. These adipose-derived factors are mainly influenced by nutritional transitions. This review addresses essentially the differential regulation ...
Societal challenges put public mental health at risk and result in a growing interest in resilience as trajectories of good mental health during stressor exposure. Resilience factors represent multilevel psychosocial resources that increase the likelihoo
Our model predicts that the majority of transcription factors that affect intron retention come from the zinc finger family. We demonstrate the validity of these predictions using ChIP-seq data for multiple zinc finger transcription factors and find strong over-representation for their peaks in intron...
Across animal models, male sexually selected traits that affect intrasexual competition and intersexual choice appear to be especially vulnerable to the EDCs that have been tested to date. EDCs also seem to exert sex-specific effects on anxiety/depressive-like behaviors in animal models and human ...
1E). Single knockdown of each gene did not affect cell proliferation while double knockdown of SMARCA2/4 significantly reduced the proliferative capacity of the cells in vitro (Fig. S1C). Pharmacological inhibition of SMARCA2/4 with FHD-286 downregulates neuroendocrine and neuronal signaling pathways...
Neurodevelopmental Disorders and Environmental Toxicants: Epigenetics as an Underlying Mechanism We then review studies showing the epigenetic effects of those environmental factors in humans that may affect normal neurodevelopment.doi:10.1155/2017/7526592... TNQ Vuong,M Kunio - 《International Journal of ...