Structure of aptamer developed by Base Pair Biotechnologies to IL-7 What is an Aptamer? The term “Aptamer” was coined by Andy Ellington. It stems from the Latin terms “aptus,” meaning to fit, and “meros,” meaning part. Aptamers are short, single-stranded DNA or RNA (ssDNA or ...
It is an EMT biomarker that maintains cell struc- ture and motility during cell migration. In the TME, it is expressed not only in CAFs, but also in epithelial cells undergoing EMT, vascular endothelial cells, and mesen- chymal-derived cells such as adipocytes and myocytes [134]. ...
Mullis's technique involvesan artificial molecule with two parts. One is called a DNA aptamer -- a long, highly folded single strand of DNA that can grab onto a unique target, not unlike an antibody. For the purposes that Mullis has in mind, that target would be a pathogenic bacterium or...
A Network of Networks to Reproduce the Electrical Features of an Aptamer-ligand Complex - What an Electrical Network Tells about Affinity... E Alfinito,R Cataldo,L Reggiani 被引量: 0发表: 2017年 Hierarchy and assortativity as new tools for affinity investigation: the case of the TBA aptamer-...
Besides the just mentioned drugs, which are all proteins targeting pan-VEGF-A isoforms, there is another drug somehow unique in its own way: pegaptanib, a 28-nucleotide RNA aptamer of ∼50 kDa with a high selectivity for the VEGF-A165 isoform. Pegaptanib sodium was registered for the treat...
Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease. Nat Rev Drug Discov. 2006;5(2):123–32. Article CAS PubMed Google Scholar Kinstler O, Molineux G, Treuheit M, Ladd D, Gegg C. Mono-N-terminal poly(ethylene glycol)-protein conjugates. Adv Drug Deliv Rev. 2002;54...
The term "aptamer" is derived from the Latin word "aptus" meaning "to fit" and a Greek word "mers" meaning "particle". Aptamers as a promising approach for the control of parasitic diseases More results ► Acronyms browser ? ▲ APTMD APTMS APTMS-TMOS APTN APTNA APTNAC aptNR1 APTO AP...
Survivin (also named BIRC5) is a well-known cancer therapeutic target. Since its discovery more than two decades ago, the use of survivin as a target for cancer therapeutics has remained a central goal of survivin studies in the cancer field. Many studie
Let’s see if proteomic clocks can catch up. The new technology is based on SOMAscan assays, and so far is marketed to research labs, not individuals or doctors, and it is priced accordingly.The only company providing lab services isSOMAlogic.comof Boulder, CO.“SOMAscan is an aptamer-based...
Aptamer Aptamer Aptamers, nucleotide Aptamers, nucleotide Aptamers, peptide Aptamers, peptide APTAN APTAP APTAS Aptate APTB APTBA APTBS APTC APTC APTCA APTD APTDA APTDC APTDE APTDL APTE Apte, Hari Narayan APTEC Aptech Aptech Computer Certified Professional Apted Apted ▼Complete...