depending on which exons are spliced back together during RNA processing. This so-called "alternative splicing" is illustrated in Figure 3. Scientists have also since learned that eukaryotic cells have evolved another "alternative" mRNA processing pathway: the use ofmultiple 3' cleavage sitesin...
Why is alternative RNA splicing in the eukaryotic cell important? What is CRISPR-Cas9? How is the technique useful for iPS cell studies? How does DNA extraction have scientific relevance? Describe example applications of genetic engineering and recombinant DNA technology. ...
Two projects, ENCODE and modENCODE, have given us an alternative view of how the genome is organized. ENCODE (the ENCyclopedia Of DNA Elements) is a public research consortium that is trying to identify all of the functional elements in the human genome. And modENCODE is doing the same ...
A. Its sequence is almost exactly identical to that of a gene in another organism. B. Its structure (meaning its pattern of exons and introns) is identical to that of What is the branch of genetics that deals with the expression of genes by studying the DNA sequences of chromo...
elegans can be usefully applied to understand the mechanisms of drug sensitivity and the genetics of resistance in parasites. This is a preview of subscription content, log in via an institution to check access. Similar content being viewed by others Caenorhabditis elegans is a useful model for ...
However, in real-life genetics, this is not the case. Instead, it has been found that multiple genes often influence specific traits in the expressed phenotype of the organism. Examples of this would be pigmentation in parts of organisms or the final size of the organism. How dominant or ...
Laser capture microdissection (LCM) is an alternative method increasingly utilized in plant transcriptomic analysis [8,9]. LCM has proven to be a valuable technique for transcriptomic analysis of phloem [10] and vascular cambium [11]. It has been employed to select vascular tissue cells in Arabid...
It is a signal that some RBD-containing MSI1 isoforms can be incompatible to ZIKV binding and replication. Consequently, the chance of ZIKV successfully infecting host cells could also be associated with alternative splicing and expression of ZIKV-compatible MSI1 isoforms in both inter and ...
Serum albumin is a major plasma protein in mammalian blood. The importance of this protein lies in its roles in both bioregulation and transport phenomena.
Alternative splicing, however, did not in itself require a drastic reappraisal of the notion of a gene; it just showed that some DNA sequences could describe more than one protein. Today's assault on the gene concept is more far reaching, fuelled largely by studies that show the previously ...