Alternative splicing, a clever way a cell generates many different variations of messenger RNAs—single-stranded RNAs involved in protein synthesis—and proteins from the same stretch of DNA, plays an important role in molecular biology. Progressing rapidly, the field of alternative splicing is a com...
How is molecular biology used in forensic science? What is the more realistic method of determining the efficacy of a chemical? How can biotechnology help the environment? What is biotechnology and its applications? Define what is an alternative hypothesis. ...
We say a cell is alive. But look inside a cell and all you will see are molecules, collections of atoms that are as inanimate as the screem in front of you. How does a set of objects make a dynamic living organism? This question is what we are talking about in molecular biology.All...
Alternative splicing of pre-mRNAs is central to the generation of diversity from the relatively small number of genes in metazoan genomes. Auxiliary cis e... AN Ladd,TA Cooper - 《Genome Biology》 被引量: 431发表: 2002年 Building a protein interaction map: research in the post-genome era....
(2008) Alternative splicing resulting in nonsense-mediated mRNA decay: what is the meaning of non- sense? Trends Biochem. Sci., 33, 385-393.McGlincy, N.J. and C.W. Smith, Alternative splicing resulting in nonsense-mediated mRNA decay: what is the meaning of nonsense? Trends in ...
"alternative" mRNA processing pathway: the use ofmultiple 3' cleavage sitesin a single exon. (Every intron has a 5' and3' splice site.) As illustrated in Figure 3, the end result is the same as with alternative splicing: different mRNA molecules are produced from a single protein-coding ...
It turns out that transcription also occurs in intergenic sequences, and transcripts have been found that span multiple genes. Transcripts from the ENCODE project show extensive alternative splicing. There have also been reports of trans-splicing in which two different primary RNA transcripts are ...
Why is alternative RNA splicing in the eukaryotic cell important? What are the characteristics of t-RNA? Why is DNA more reliable than RNA? What are the essential features of RNA? What is the difference between RNA and DNA? What are the main differences between DNA and RNA?
Regulation of expression by transcription factors and by alternative splicing are two different mechanisms of controlling gene expression in eukaryotes. What is the fundamental difference between the two? What are the enzymes involved in DNA transcription?
due to several limitations, microarray technology is being increasingly replaced by other high-throughput gene expression methods. This is primarily due to the limitations of microarrays in analyzing unknown genes, as well as difficulties in detecting multiple transcripts formed by alternative splicing [...