What is Cabazitaxel? The taxane derivative cabazitaxel (JevtanaR) is approved in the USA and the EU for use in combination with prednisone for the treatment of patients with hormone-refractory metastatic prostate cancer... Feb 11,2020Antineoplastic agents Bioactivity of Benzo(k)fluoranthene Benzo...
It is licensed as a first-line treatment in combination with ▼paclitaxel for those whose cancer cells overexpress HER2 and for whom an anthracycline is unsuitable, and as a third-line treatment used alone when treatment with (where appropriate) an anthracycline, a taxane and hormonal therapy has...
One dose of human papillomavirus vaccine (HPV) vaccine can prevent infection for at least 3 years, and maybe even longer; Eli Lilly plans to seek FDA approval for Alzheimer drug that slows decline; New York governor signed a bill expanding contraceptive access in the state next year...
Chemotherapy in Androgen-Independent Prostate Cancer (AIPC): What's next after taxane progression? Prostate cancer is the most common non-cutaneous cancer in the United States. Although most are diagnosed at earlier stages of disease, a significant numbe... JB Aragon-Ching,WL Dahut - 《Cancer ...
Neoadjuvant chemotherapy is the standard of care for patients with large, inoperable tumors or inflammatory breast cancer, but it is also increasingly considered for women with operable disease. Several randomized trials have demonstrated that anthracycline- and taxane-containing regimens in operable breast...
dyspnea within a few hours after taking the drug. This dyspnea is often short-lived and has mild symptoms. It rarely requires dose adjustment and most does not require special treatment. Its pathogenesis is unclear and its relationship with gemcitabine Not sure either....
Van Cutsem, J.A. Ajani, H. Castro, et al. Trastuzumab emtansine versus taxane use for previously treated HER2-positive locally advanced or metastatic gastric or gastro-oesophageal junction adenocarcinoma (GATSBY): an international randomised, open-label, adaptive, phase 2/3 study Lancet Oncol, ...
Even though the Food and DrugAdministration has retracted approval of angiogenesis inhibitors in breast cancers, there may be an indication for it in the triple negative breast cancers. As bevacizumab is used in glioblastoma multiforme, there may be a need for it in CD44 high, CD24 low,...
Office passage to India: India is proving a popular destination as British companies discover how cheaply they can run operations like call centres there. ... Taxane based chemotherapy is the standard of care treatment in castration resistant prostate cancer (CRPC). There is convincing evidence ...
Unfortunately, this study was almost negative [29] because the mOS was 17.5 months in experimental arm versus 14.2 in the standard (HR: 0.84; p = 0.0565), a difference that did not find statistical significance. Trastuzumab-emtansine (TDM-1) is an antibody-drug conjugate that is widely used...