A Hematopoietic Stem Cell Transplant Quality, Clinical, Cellular Dashboard: What Is The Evidence?Identifying HSCT clinical, quality, cellular indicators with valid benchmarks is essential to evaluate quality of
A common statement is “The only risk is that it won’t work.” That’s false. 3) The only stem cell treatment explicitly OK with the FDA for use in the U.S. consists of versions of cord blood/bone marrow/hematopoietic stem cell transplantation. What this means is that any other ...
Multiple myeloma (MM) is the most common form of plasma cell malignancy, accounting for about 1.7% of all malignant tumors [1]. Although the use of a variety of treatment options such as high-dose chemotherapy, hematopoietic stem cell transplantation (HSCT), proteasome inhibitors (PIs), immunom...
Apoptosis is strictly regulated by enzymes known as caspases which cleave the proteins in the cells when activated. Caspases are present in an inactive form in all cells, and when a caspase is activated, it triggers a cascade of downstream activity in all the caspases present in the cell. Th...
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative treatment for over 70 benign and malignant hematologic and immunological processes. Over the past several decades, significant technological and post-transplant supportive advances have been made, resulting in a decrease...
What is a stem cell transplantation? A stem cell transplant is a procedure in which a patient receives healthy stem cells to replace damaged stem cells. The stem cells may come from the patient's own body (autologous) or from a donor (allogeneic). Before the transplant, the patient receives...
cells that is present in the literature makes one wonder whether it is possible to provide a unified stem cell concept. To be satisfactory, such a concept should accommodate all our current knowledge about stem cells and simultaneously serve stem cell biologists as a guide to conduct their ...
For instance, a multipotent blood stem cell is a hematopoietic cell that can differentiate into several types of blood cell types (such as neutrophils and lymphocytes) but cannot differentiate into brain cells, bone cells or other non-blood cell types. In the bottom of the differentiation ...
SCID can be treated with hematopoietic stem cell transplant (HSCT) (a bone marrow transplant). The following table summarizes the difference between CVID and SCID. Summary – CVID vs SCID Primary immunodeficiency diseases are disorders in which a part of the body’s immune system does not functio...
Where in the body are hematopoietic stem cells found? What types of cells provide support for an herbaceous stem? What is the main unique property of stem cells? What are the two regions of the brain stem? How many stem cells are found in bone marrow?