What happens in the synapse and at the post-synaptic membrane when: A. acetylcholine is released into the synapse? B. a cholinergic receptor antagonist is found in the synapse? C. an acetylcholinesterase inhibitor is found in the synapse? D. a GABA recept ...
A) G-protein coupled B) beta-adrenergic C) ionotropic D) dopaminergic E) muscarinic cholinergic A drug that blocks the effect of another drug by binding to its receptors is called a(n): a. mediator b. receiver c. antagonist d. agonist What are the drugs that speed up the...
In this lesson, we will learn the definition of loratadine, review reasons for which it is taken, and discuss possible side effects. We will also examine the class of drug it belongs to. Case Study Callie is a 20-year-old female who presents to the clinic with complaints of itchy, water...
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Using the intravenous self-administration procedure in rats, we demonstrated that admin- istration of the mGlu5 receptor antagonist MPEP (6-methyl-2- [phenylethynyl]-pyridine), the competitive NMDA receptor antago- nist LY235959, or the AMPA/kainate receptor antagonist NBQX, either systemically or ...
Alzheimer's disease (AD) is the most commonly occurring age-related neurodegenerative disease and the most frequent cause of dementia among the elderly. The cognitive deficits of the disease are thought to be primarily related to the degeneration of cholinergic neurons in the cortex and hippocampus,...
Among the neurotransmitters involved in addiction, dopamine (DA) is clearly the best known. The critical role of DA in addiction is supported by converging evidence that has been accumulated in the last 40 years. In the present review, first we describe the dopaminergic system in terms of conne...
An antagonist of the dopamine D3 receptor, mesdopetam, is currently being evaluated for its effects on dyskinesia in a phase 2b study (NCT04435431). Previous studies in rodent models and a phase 1 study indicated a possible anti-dyskinetic and antipsychotic effect without deterioration of motor ...
Adrenaline: Adrenaline or epinephrine is also called a stress hormone because the adrenal medulla secretes it during stressed conditions. This gland is located above the kidney. The receptors of epinephrine hormone are called adrenergic receptors...
Methadone is a very powerful drug that is often used as a substitute for other more common opioid painkillers. This lesson will define methadone in more than one way so you understand all of its aspects and describe its basic mechanism of action. Related...