P53 is found often in familial melanoma cases. The gene, when it operates normally, helps the body repair mutated cells to prevent, amongst other things, cancer from developing. However when p53 is altered it can’t operate its job properly and allow cancers to grow. Heavy UV light that da...
What happens to the cell cycle if both p53 alleles are mutated? a. What would happen if mitosis occurred without stopping? b. Which types of cells undergo mitosis and why? c. Why do they stop and what might happen if they didn't? If we stop cell division, what will happen to our a...
In accord- ance with the results of this study, if smoking is not present, a larger indoor radon concentration seems to be necessary to induce lung cancer [25–27] compared to what happens in former smokers. This study also observed that radon con- centration appeared to be associated with...
What is the role of the p53 gene, and what happens when it mutates? Explain how inheritance of a gene that increases the risk of cancer does not lead to the certainty of cancer. In this paragraph, include a discussion of the steps that need to occur from a cellula...
energy and multiply. For example, in some cancers, the ras gene (an oncogene) is mutated, and produces a protein that stimulates cells to divide prematurely. Other oncogenes, such as C-myc and C-erb B-2, when amplified, are implicated in small cell lung cancer and breast cancer, ...
What happens if cell cycle regulators don't function properly? What are the two major ubiquitin ligases that play a central role in the control of cell cycle progression? What is the control center of the cell that is necessary for cell division and cell life?
What happens when a mutation results in an amino acid substitution? A mutation has occurred in the promoter sequence of a gene. Briefly explain what effect that mutation will likely have on the transcription of the gene. Fill in the blank with correct word/s. In a protein ...
What happens to the cell cycle if both p53 alleles are mutated? Which of the following is typical of cancer cells? a. Products of oncogenes inhibit mitosis. b. Benign tumors invade normal tissue. c. Malignant cells migrate. d. Cancer cells lose the ability to divide. e. The parent...
What happens to the cell cycle if both p53 alleles are mutated? Which type of cells within our bodies use mitosis to reproduce? What are the two stages of the cell cycle? When does DNA replication occur? What ways can cell division and the cell cycle go wrong...
What happens when tumor suppressor genes are damaged? Why are inherited cancers tumor suppressor genes? Do tumor suppressor genes cause cell proliferation? Why are proto-oncogenes and tumor suppressor genes related to cancer? How is p53 related to oncogenes and tumor suppressor genes? How do p53...