2022). Clozapine and quetiapine (off-label) are currently the main drug treatments of PD psychosis due to their low risk of worsening extrapyramidal symptoms (Seppi et al. 2019). Still, medication with atypical antipsychotics may lead to an increased mortality and severe adverse effects in PD ...
Clozapine use in patients with schizophrenia and the risk of diabetes, hyperlipidemia, and hypertension: a claims-based approach Arch Gen Psychiatry, 58 (2001), pp. 1172-1176 View in ScopusGoogle Scholar [73] D.J. Malenka, A.V. Kaplen, F.L. Lucas, S.M. Sharp, J.S. Skinner, et al...
Among the neurotransmitters involved in addiction, dopamine (DA) is clearly the best known. The critical role of DA in addiction is supported by converging evidence that has been accumulated in the last 40 years. In the present review, first we describe the dopaminergic system in terms of conne...
Patients taking drugs with a narrow therapeutic index metabolized by CYP1A2 (e.g. theophylline and clozapine) should avoid taking them with E. purpurea. However, studies conclude that no clinically significant interactions were expected between E. purpurea and substrates of CYP2D6, CYP2C19 and CYP...