such as certainautoimmune disorders, diabetes, high blood pressure, heart disease,frequent urinary tract infections, or a history of smoking. You may also get an eGFR test if other people in your family have diabetes or kidney disease.
How does the glomerulus "autoregulate" the filtration rate locally? What is the difference between eGFR and GFR? What factors are taken into consideration when calculating both? List six factors that affect the rate of osmosis. Discuss the laboratory investigations that can be used to meas...
dyslipidemia, type 2 diabetes mellitus, and cardiovascular disease. Therefore, there is an inevitable need for measures to manage obesity and its related disorders. At this point, MD has been proposed as a valuable nutritional intervention. It is characterized by a high consumption of ...
FDA approved indication, hypermutation in gliomas tends to be subclonal and does not generate optimal anti-tumor responses, and therefore the response rates to checkpoint blockade may still be limited [26]. So, despite the fact that hypermutation may occur in the recurrent setting, in the Checkma...
Functional imaging biomarkers have the potential to quantify biological characteristics of tumours and measure on-target and off-target effects that indicate early likelihood of response to a specific therapy, which can then be used to guide the optimal biological dose and drug schedule. Serial, non...
What does diminished kidney function mean? A severe decrease in kidney function can lead toa buildup of toxins and impurities in the blood. This can cause people to feel tired, weak and can make it hard to concentrate. Another complication of kidney disease is anemia, which can cause weakness...
The patients with high microsatellite instability (MSI-H)/mismatch repair deficient (dMMR) tumors recently have been reported that can benefit from immunotherapy, and MSI can be used as a genetic instability of a tumor detection index. However, many stud
How long does COVID aching last? Aches or muscle pains may be an early sign of COVID-19, often appearing at the very start of the illness and lasting for an average of 2-3 days. Unfortunately, aches related to the coronavirus can sometimes last much longer and are commonly reported in...
handgrip strength (HGS) and performance tests (sit-to-stand-chair-test and 6-min-walk-test) were significantly lower in the older senior CKD patients [52]. A study based on the EQUAL study (n = 1334) showed that the risk of PEW in CKD patients with eGFR < 20 ml/min incre...
One of the most important reasons why the treatment with Platinum derivatives is abandoned or does not bring the expected results is the phenomenon of resistance. This phenomenon makes further treatment, eg with Cisplatin, ineffective and another effective therapy must be found. Such a solution may...