Next-generation sequencing (NGS) is a technology for determining the sequence of DNA or RNA to study genetic variation associated with diseases or other biological phenomena. Introduced for commercial use in 2005, this...
In 1991, Roche saw the potential in PCR and invested in refining the science for use in molecular diagnostics to detect pathogens and genetic code changes that lead to diseases. Roche has not only refined PCR,but it has remained the clear leader and innovator of this technology. ...
A blood test can detect the presence of HDV antibody, which indicates a past or current infection. A polymerase chain reaction (PCR) test detects the level of HDV in blood and is used to diagnose a current HDV infection. International guidelines for HDV testing vary from testing all individual...
The symptoms of many arboviral diseases are similar, so diagnosis may be challenging. If your doctor suspects KFD, though, they can confirm it with laboratory tests focused on: Molecular detection based on the polymerase chain reaction (PCR) Virus isolation from the blood Serologic testing usingen...
SNP-based strain detection is relevant in both clinical and agricultural research and has been used to study a range of infectious diseases in both humans and plants Top Using real-time PCR to perform SNP genotyping Real-time PCR enables you to scre...
Today, blood tests can do many things, because doctors and scientists have identified many substances in the blood that can tell you if you have an infection, an autoimmune disease, a marker for cancer, inherited diseases, and even blood clots or heart failure. Blood tests are also used to...
and human T-cell lymphotrophic virus I (HTLV-I), which causes leukemia. Reverse transcriptase is also a fundamental component of a laboratory technology known as reverse transcription-polymerase chain reaction (RT-PCR), a powerful tool used in research and in the diagnosis of diseases such as ...
How can we use it? What is LAMP assay? LAMP assay , Loop-mediated isothermal amplification test, is a single-tube technique for the amplification of DNA and a low-cost alternative to detect certain diseases. Reverse transcription loop-mediated isothermal amplification (RT-LAMP) combines LAMP with...
The Sanger method has also been used to diagnose diseases and develop new drugs. Polymerase Chain Reaction (PCR) Doctor Kary Mullis invented polymerase chain reaction (PCR). PCR works by repeatedly heating and cooling DNA. When DNA is heated, it separates into two single strands. Next, an ...
Some monogenic diseases are fatal, while others can be managed with treatment. Candidates for PGT-M Include: PGT-M can be a valuable tool for couples who risk passing on a genetic disease to their children. Here are some of the factors that may make a couple good candidates for PGT-M: ...