Articular cartilage can be damaged through accidents, such as a tear to the anterior cruciate ligament (ACL), or degenerate slowly over time, eventually leading to osteoarthritis. Poor alignment of the joint, excessive weight, excessive activity, overuse, or injury can all cause cartilage to wear ...
Cartilage is defined as a type of connective tissue that provides structural support and protection for the body's joints. Explore more at BYJU’S Biology
In osteoarthritis (OA) joint articular cartilage fails. While the etiology of cartilage failure in OA is still controversial, some of the mechanisms responsible for loss of proteoglycans from these tissues have been identified and offer insights for potential avenues of therapeutic control. Many non-...
Unfortunately, stem cells used for cartilage repair seem to have a similar fate, making the repair tissue inadequate for normal joint function (2). How the articular chondrocyte avoids this and maintains its specialized phenotype is one of the fundamentally important issues in skeletal biology, yet...
Cartilage collagens: What is their function, and are they involved in articular disease? Arthritis Rheum. 32, 241- 246.Mayne R (1989) Cartilage collagens: what is their function, and are they involved in articular disease. Arthritis Rheum 32:241–246Mayne, R . 1989 . Cartilage collagens ...
Type 10/Type X:Type 10 helps with new bone formation and forming articular cartilage. It’s involved in the process of endochondral ossification, which is how bone tissue is created in mammals. It’sbeen found to be beneficialfor bone fracture healing and repairing of synovial joints. ...
In a study of 44 first-time marathon runners (17 men and 27 women), researchers noted that post-marathon: “The knees of novice runners achieved sustained improvement, for at least 6 months post-marathon, in the condition of their bone marrow and articular cartilage.” Same goes for the lo...
Molecular transport in articular cartilage — what have we learned from the past 50 years?Developing therapeutic molecules that target chondrocytes and locally produced inflammatory factors within arthritic cartilage is an active area of investigation. The extensive studies that have been conducted over ...
R. Mayne, "Cartilage collagens. What Is Their Function, and Are They Involved in Articular Disease?," Arthritis and Rheumatism 32, 241-246 (1989).Mayne R. Cartilage collagens:what is their function,and are they involved in cartilage disease[J].Arthritis and Rheumatism,1989,(03):241-246....
The Damage and Loss of Joint Cartilage The defining feature of osteoarthritis is the breakdown and loss of articular cartilage. This strong, smooth, slippery cartilage normally covers the surfaces of bones where they meet at joints—for example, the bottom of the femur (thighbone) and top of ...