Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel virus responsible for the current coronavirus disease 2019 (COVID-19) pandemic, has infected over 3.5 million people all over the world since the first case was reported from Wuhan, Ch
If a patient has a sulfa allergy the previous 2 options are not suit- able, but this one may be. Invokana works by inhibiting the sodium glucose cotransporter 2 (SGLT2), which causes a reduction in the reabsorption of filtered glucose. The drug also causes the patient to excrete excess gl...
There are 5 stages of CKD. The diet changes you need to make are based on your stage of kidney disease. Work with your dietitian or healthcare provider to plan meals that are right for you. You may need any of the following:Limit protein in all stages of kidney disease. Limit the ...
In recent years, a number of drugs have emerged that have significant cardio-renal protective effects in patients with diabetes, and a typical example is sodium-glucose cotransporter 2 inhibitor (SGLT2i), glucagon-like peptide-1 receptor agonist (GLP-1RA), and nonsteroidal mineralocorticoid ...
Despite the recent expansion of antidiabetic agents such as GLP-1 receptor agonists and SGLT-2is, glycemic control remains suboptimal in many patients. Approximately half of all type 2 diabetic patients in the United States and worldwide fail to achieve the glycemic target of A1c ≥ 7.0% ...
Sodium-glucose co-transporter-2 (SGLT2) inhibitors are associated with an increased risk of DKA in people who are unwell. SGLT2 inhibitors can have severe adverse effects in acute sickness during Covid-19, and modification of medication is advised (Boulto...
The main potential danger regards medications, where doses may need to be adapted. In particular, insulin doses may need to be lowered to avoid low blood sugar, and SGLT2 inhibitors may need to be de-prescribed. Learn more Discuss any changes in medication and relevant lifestyle changes wi...
Many people diagnosed with the most common form of diabetes (type 2) never regain their previous health. Instead, the “natural course” is that they are expected to become a little sicker every year, needing more and more drugs. And at some point serious complications may emerge: Blindness....
The EMPA-REG OUTCOME trial is part of the new wave of cardiovascular (CV) outcome trials required by the US Food and Drug Administration (FDA) for all new diabetes drugs.Empagliflozinis in the relatively new class of antihyperglycemics known as sodium-glucose cotransporter 2 (SGLT2) inhibitors...
What’s your sense of the best sequence of these drugs?Jennifer Sipos, MD: I don’t know of any head-to-head studies looking at that specifically, and there are very few studies in general. This is largely 1 of those issues that falls under the category of how you like to do it. ...