but the effects also persist over time for subjects who experienced amild infectionthat did not require admission to hospital. This means that PASC, especially when occurring after a mild or moderate COVID-19 infection, shares many of the same characteristics as chronic diseases triggered by ...
Most strategies to prevent, control, and eradicate COVID-19 are established based on the specific characteristics of the pathogen. The quest for interruption and eradication of COVID-19 has moved research forward in understanding fundamental aspects of the virus genome, proteome, replication mechanisms...
Antimalarial drugs (ADs) have been used in the treatment of immuno-inflammatory arthritis (IIA) and coronavirus infection (COVID-19). The aim of this review is to analyze the current knowledge about the immunomodulatory and antiviral mechanisms of action, characteristics of use...
An important challenge during the COVID-19 pandemic has been to understand asymptomatic disease and the extent to which this may be a source of transmission. As asymptomatic disease is by definition hard to screen for, there is a lack of clarity about th
The Origin and the Initial Spreading of the Pandemic Coronaviruses Detection of SARS-CoV-2 in Clinical Specimens Infections Death Rates Viral Infection, Routes of Transmission, and Window of Infectivity Public Health Considerations Public Health Measures in Countries That Have Been Able to Contain the...
Tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral ribonucleic acid (RNA) using reverse transcription polymerase chain reaction (RT-PCR) are pivotal to detecting current coronavirus disease (COVID-19) and duration of detectable virus indicating potential for infectivity. Metho...
Based on these mutations, it is thought that the Omicron variant may have similar characteristics to all other variants, at least at the molecular level [8]. All SARS-CoV-2 RT-PCR diagnostics currently detect this variant. One of the three target genes has been identified in several ...
Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the lombardy region Italy JAMA (2020 Apr 6), 10.1001/jama.2020.5394 Google Scholar 28 J. Zhu, P. Ji, J. Pang, et al. Clinical characteristics of 3,062 COVID-19 patients: a meta-analysis...
The emergence in Britain and South Africa of two new variants of SARS-CoV-2, which are potentially far more infectious versions of the virus, has prompted widespread concern. Here is what we know—and what we don't—about the mutations.
Associations between care home characteristics, reported infection, prevention and control interventions, and COVID-19 status were described and analysed. Findings No resident developed COVID-19 symptoms during the study. There was no significant difference between: the number of care homes containing ...