These conformational changes in ACE-2 binding site of SARSCoV- 2 were attributed to a greater number of contacts forming between RBD and active binding site when compared to that of SARSCoV and could explain any differences in the effectiveness of drugs against SARS-CoV and ...
Moreover, many SARS-CoV-2 infected patients are reported to develop low-titer neutralizing antibody and usually suffer prolonged illness, suggesting a more effective SARS-CoV-2 immune surveillance evasion than SARS-CoV. This paper summarizes the current state of art about the differences and ...
2.3. Determination of Pearson correlation coefficient (PCC) of DEPCGs and construction of human-SARS-CoV and human-SARS-CoV-2 co-expression networks Each DEPCGs data was formatted uniformly and their correlation profiles were measured by calculating the Pearson Correlation Coefficient (PCC) between ea...
Data were retrieved from the 2022 Japan COVID-19 and Society Internet Survey. We analyzed the self-reported SARS-CoV-2 infection as of October 2022. We included 21,875 participants aged 20–64 years. Participants were classified into five occupation groups (“medical workers,”“off-site medica...
The recent outbreak of infections and the pandemic caused by SARS-CoV-2 represent one of the most severe threats to human health in more than a century. Emerging data from the United States and elsewhere suggest that the disease is more severe in men. Knowledge gained, and lessons learned, ...
Various biological pathways may contribute to the differing responses to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus by sex. The size and independence of the effect of sex on the association between biomarkers and COVID-19 health outcomes, however, rarely have been rare...
Evidence-based public health approaches that minimize the introduction and spread of new SARS-CoV-2 transmission clusters are urgently needed in the United States and other countries struggling with expanding epidemics. Here we analyze 247 full-genome SA
SARS-CoV-2 and SARS-CoV have more than 85% identical nucleic acid sequences [5]. Therefore, the epidemiological risk factors may be similar between SARS-CoV and SARS -CoV-2. In addition to age, epidemiological studies showed that the inci- dence and mortality of SARS-CoV infection were ...
In April 2020, multiple reports of an association between a hyperinflammatory, Kawasaki-like condition and SARS-CoV-2 were published and termed as pediatric inflammatory multisystem syndrome (PIMS) or multisystem inflammatory... L Hoste,RV Paemel,F Haerynck 被引量: 0发表: 2020年 Multisystem ...
Educational differentials in key domains of physical activity by ethnicity, age and sex: a cross-sectional study of over 40 000 participants in the UK hous... To assess whether educational differentials in three key physical activity (PA) domains vary by age, sex and ethnicity.National cross-...