Basic Fibroblast Growth Factor Inhibitor Basicfibroblast growth factor (FGF), also known as bFGF and FGF2, is a member of the fibroblast growth factor family. There are two inhibitors which affect the actions of FGF2: PD 173074 and SU 5402. PD 173074 is an inhibitor of FGFR1. It can pote...
circ_0003611 miR-383–5p/KIF1B SH-SY5Y and SK-N-SH cells treated with Aβ Up Aβ-mediated cell proliferation, apoptosis, inflammatory response, oxidative stress, and glycolysis were abolished [78] 2.6. Other circRNAs' impact on AD There are many other circRNAs that participate in the occurr...
Note: Not all fungi are as well studied as this one. This article isn’t a blanket declaration that all “medicinal” mushrooms work or have any benefits at all. We follow the science on this one. And we recommend you do as well. However, that being said, there is no downside to in...
adifferential modulation of catecholamines by chlorotruazine herbcides in PC12 cells in vitro 儿茶酚胺的有差别的模块化由chlorotruazine herbcides在PC12细胞体外[translate] aGelling drum 形成胶冻的鼓[translate] aData Llnk 数据Llnk[translate]
Acta Pharmacologica Sinica npg 94 www.nature.com/aps D'Onofrio PM et al While necrosis is more dominant in the ischemic core, apop- tosis becomes more common in the penumbra as the cells are found further away from the core[2]. Apoptosis is a normal process during development, and is ...
To date, the underlying mechanisms of these opposing effects are not well understood and require further investigation. Several strategies are currently used to inhibit CREB function in tumor cells: (1) Initial studies focused on domi- nant negative CREB mutants (KCREB) to...
(14.7±1.05).The percentage of apoptosis cells in 50μM group(28.6±1.92) and 100μM group(38.7±1.32) are much higher than the control group. Abnormal apoptosis was induced in 250μ 分析由流程cytometry显露的在50μM小组28.6±1.92中显著增加了apoptotic PC12细胞的百分比,除了(10μM) ATR治疗...
Ras-dependent growth factor regulation of MEK kinase in PC12 cells. Science 1994; 265:1458–1461 Article PubMed CAS Google Scholar Xing J, Kornhauser JM, Xia Z, et al. Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to ...
Crispo JA, Ansell DR, Piche M, Eibl JK, Khaper N, Ross GM, and Tai TC. “Protective effects of polyphenolic compounds on oxidative stress-induced cytotoxicity in PC12 cells.” Can J Physiol Pharmacol 88: 429-438 (2010). Romier B, Van De Walle J, During A, Larondelle Y, and Schn...
Some of them such as CLN1 (palmitoyl protein thioesterase 1), CLN2 (tripeptidyl-peptidase 1), CLN5, CLN10 (cathepsin D), and CLN13 (cathepsin F), are lysosomal soluble proteins; others like CLN3, CLN7, and CLN12, have been proposed to be lysosomal transmembrane proteins. In this ...