Sequence motifs are short, recurring patterns in DNA that are presumed to have a biologi- cal function. Often they indicate sequence- specific binding sites for proteins such as nucleases and transcription factors (TF). Others are involved in important processes at the RNA level, including ...
Eisen,M. (2005) All motifs are NOT created equal: structural properties of tran- scription factor-DNA interactions and the inference of sequence ... MB Eisen - 《Genome Biology》 被引量: 80发表: 2005年 Detecting seeded motifs in DNA sequences The problem of detecting DNA motifs with functi...
Genome editingis a type of geneticengineering where a DNA is inserted, deleted or replaced in the genome of aliving organism. The application of this technology has revolutionized variousresearch areas ranging from biomedicine to biotechnology or synthetic biology.A key point to initiate the editing ...
aLeading Greek jeweller Lalaounis’ exquisitely crafted creations reflect ancient Greek motifs and draw inspiration from other cultures, biology, nature and mythology. 主导的希腊珠宝商Lalaounis’精妙地被制作的创作反射希腊语主题并且从其他文化、生物、自然和神话得出启发。 [translate] aгорячейв...
Of course, biology is never that simple. It turns out that CR domains are likely multi-functional, with distinct activities dependent upon other nearby motifs or sequences. Using a series of deletions, point mutations, and CR domain swaps in Drosophila, Yu et al. show that a construct contai...
https://pdbj.org- Website for the PBDj (Protein Data Bank Japan) which supports browsing in multiple languages such as Japanese, Chinese, and Korean; SeSAW identifies functionally or evolutionarily conserved motifs by locating and annotating sequence and structural similarities, tools for bioinformatic...
Currently, adjuvants such as aluminium salts, Toll-like receptor agonists, liposomes, immunostimulating complexes (ISCOM), and CPG motifs synergistically induce a potent immune response80. However, there are some emerging issues with the addition of adjuvants. For example, the uniformity of aluminium...
Amino Acid MotifsAdenosine TriphosphatasesThe 伪-helical solenoid proteins adopt a variety of elongated curved structures. They have been examined to identify the interactions that determine their curvature. A sequence pattern characteristic for strongly curved 伪-helical solenoids has been constructed and ...
Ubiquitin-binding domains (UBDs) are a collection of modular protein domains that non-covalently bind to ubiquitin. These recently discovered motifs interp... Linda,Hicke,Heidi,... - 《Nature Reviews Molecular Cell Biology》 被引量: 1217发表: 2005年 A SUMO ligase is part of a nuclear multi...
Replacement of a Drosophila Polycomb response element core, and in situ analysis of its DNA motifs. Mol. Genet. Genom. 279, 595–603 (2008). CAS Google Scholar Sing, A. et al. A vertebrate Polycomb response element governs segmentation of the posterior hindbrain. Cell 138, 885–897 (...