关键词: CD4-Positive T-Lymphocytes Animals Humans HIV-1 HIV Infections Simian Acquired Immunodeficiency Syndrome Lymphocyte Activation Immunologic Memory Simian immunodeficiency virus T-Lymphocytes, Regulatory DOI: 10.1586/14760584.7.2.155 被引量: 13 ...
Male patients, which received a heart from a female donor, showed Y chromosome-positive cells both in the myocardium (cardiomyocytes) and in the vessel wall (smooth muscle and endothelium). Those findings of primitive cells from the recipient (XY) in the grafted heart (XX) demonstrated that ...
Tumor infiltrate of memory CD8 T cells and CD45RO memory T cells may predict recurrence: The role of cytotoxic CD8 T cells has been widely studied in CRC. Tumor-infiltrating lymphocytes (TILs) are central to the antitumor immune response. The prognostic role of the immune response has been ...
characterized SSCs in perivascular regions in bone marrow as CD45−TER119−Sca-1+CD140a+ cells [10]. Ambrosi et al. showed that CD45−CD31−Sca-1+CD24+ cells from the same compartment are able to differentiate into more committed adipogenic and osteochondrogenic progenitors (CD45−...
Abnormal tumor microenvironment and immune escape in multiple myeloma (MM) are associated with regulatory T cells (Tregs), which play an important role in maintaining self-tolerance and regulating the overall immune response to infection or tumor cells.
SHED show positive expression for the embryonic markers OCT4 and NANOG, mesenchymal stem cell markers STRO-1 and CD146, and tumor recognition antigens TRA-1-60 and TRA-1-81, but negative expression of hematopoietic markers such as CD45, CD11b/c, and HLADR [11,23]. Show abstract Long ...
MSCs are a subset of stem cells from the stroma of BM as well as other sources, such as adipose tissues, cord blood and placenta, that are positive for CD44, CD54 and CD105, but negative for HSC markers CD34 and CD133. In the BM, they account for only about 0.01% of the BM mono...
the underlying molecular mechanisms driving that process are still a matter of debate as is the role of stem cells therein. Furthermore, the aging of skin is peculiar as it is not only driven endogenously but is largely accelerated and aggravated by external influences, mainly, UV radiation, w...
Are the UCP-1+ cells in humans equivalent to rodent brown adipocytes, or are they more similar to beige cells? Several groups have tackled this issue and have come to different conclusions based on the relative expression of these and other marker genes. The interscapular brown fat of human...
The number of CD45 positive cells (green, arrows) was quantified and calculated as percentage of total cells (DAPI, blue). Scale bar = 100 μm (n = 3). (E) SR staining and quantification of positive areas after withdrawal of WD. Scale bar = 100 μm (n = 3–6). ** p < 0.01...