There is a wide variation in the number of CD34+ cells infused for an autologous transplantation. While the minimum number of hematopoietic stem cells for a successful transplantation has been established, there is no definite information on the optimum number or the maximum number of stem cells....
athe expression of endothelial-specific markers like FLT-1 KDR, ICAM-1 increased after exposure to VEGF together with the occurrence of CD34 and von Willebrand Factor positive cells. 内皮细胞具体标志表示喜欢FLT-1 KDR,在对VEGF的暴露以后被增加的ICAM-1与CD34和冯Willebrand Factor正面细胞一起发生。[...
A. Comparative biology of mouse versus human cells: modelling human cancer in mice. Nature Rev. Cancer 3, 952–959 (2003). Article CAS Google Scholar Hiramatsu, H. et al. Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/γcnull mice model. ...
While the above described contra- dictions make it difficult to draw solid conclusions on the oncogenic potential of the MLL-AF4 fusion protein itself, there is another important question to be asked and answered: Are these MLL- AF4-driven leukemogenesis studies targeting the right cells? In ...
Very early cART could reduce the frequency of HIV-1 DNA-positive cells significantly, but this effect is probably less pronounced if treatment is initiated in later stages of the infection [100]. Even when cART is started during the acute infection phase of the disease, no further decay of ...
5) Stem cells are not a cure-all. I am as excited as anybody about the potential of stem cells to treat a whole bunch of diseases and injuries, but they are not some kind of miracle cure for everything. When a doctor offers to inject some kind of stem cells into a patient either ...
lymphoplasmacytic infiltrates localized to stroma and tumor parenchyma. (B) Moderate differentiated tumor cells forming thick trabeculae in the tumor. (C) Hepatocyte-like tumor cells with round nuclei and eosinophilic cytoplasm. (D) Tumor cells are strongly positive for CK7. (E) HepPar1 is also...
2005). This is remarkable, since sections of primary tumors often show a mosaic of TF-positive and TF-negative cells (which is to be expected if TF is a CSC marker). In the light of our hypothesis the expression of TF on DTC might be interpreted as indicating that these cells are ...
positive) Inflammatory myofibroblastic tumor Inflammatory fibroid polyp (may have PDGFRA mutations) Solitary fibrous tumor Synovial sarcoma Dedifferentiated liposarcoma Endometrial stromal sarcoma Sarcomatoid carcinoma Abbreviations: GIST, gastrointestinal stromal tumor; ICC, interstitial cells of Cajal; PDGFRA, ...
Thus, does a long-lived population of mTreg cells exist? In this review, we would like to discuss the concept of regulatory memory and in which tissues mTreg cells can perform their functions. Box 1. Regulatory T cells. Regulatory T cells (Tregs) are a specialized subset of ...