(CBP). Transcriptional activator that couples chromatin remodelling to transcription factor recognition. CBP and its close relative p300 have histone acetyltransferase activity. SET domain (Su(var)3–9, E(z), Trx domain). A conserved 130–140 amino acid domain, which was initially characterized in...
Transcription activator proteins bind to [{Blank}] on DNA. What is transcription? Describe the process of transcription. Where does it occur? What enzyme(s) are involved? What is the product(s)? What are the transcription start and stop signals in eukaryotes and prokaryote...
What proteins are not made at the rough ER?Answer and Explanation: Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your tough homework and study questions. Ask a question Search Answers...
The catabolite activator protein (CAP) is expressed and forms a complex with cyclic adenosine monophosphate (cAMP). cAMP is a molecule that is present in high concentrations when glucose levels are low. This double requirement prevents the lac operon from being expressed when an easier to metaboliz...
(Open in a new window)PubMed(Open in a new window)Web of Science ® Macor P, Durigutto P, Argenziano M, et al. Plasminogen activator-coated nanobubbles targeting cell bound β2-glycoprotein I as a novel thrombus-specific thrombolytic strategy.Haematologica...
Abnormal tumor microenvironment and immune escape in multiple myeloma (MM) are associated with regulatory T cells (Tregs), which play an important role in maintaining self-tolerance and regulating the overall immune response to infection or tumor cells.
Epilepsy, one of the most common neurological diseases, affects more than 70 million people worldwide. Anti-seizure drugs targeting membrane ion channels or GABAergic neurotransmission are the first choices for controlling seizures, whereas the high inci
Estrogen receptors are highly expressed in osteoblasts, osteoclasts and osteocytes, and have protective effects on bones. Estrogen binds to the estrogen receptor, which regulates the expression of proteins encoded by estrogen target genes, such as insulin-like growth factor 1 (IGF1) and transforming...
kines involved in inflammation and hemostasis: growth factors (TNF伪, transforming growth factor-beta, nerve growth factor, VEGF), cytokines (IL-1尾, IL-6, IL-10), chemokines (IL-8), acute-phase proteins (haptoglobin, serum amyloid A) and prothrombotic factor (plasminogen activator inhibitor-...
Moreover, in these hESCs, MLL-AF4 appeared to act as a global transcriptional activator, positively regulating homeobox gene expression, which is in line with what is usually (but Cell Research | Vol 22 No 6 | June 2012 not always) observed in primary t(4;11)- positive infant ALL ...