Redox-regulated transactivation of activator protein-1 (AP-1) in the paraventricular nucleus (PVN) mediates renovascular hypertension (RVH)We have previously shown that RVH is characterized by increased superoxide (O) production and activation of the transcription factor AP-1 ...
Ixodes scapularis ticks transmit several pathogens to humans including rickettsial bacterium, Anaplasma phagocytophilum. Here, we report that A. phagocytophilum uses tick transcriptional activator protein-1 (AP-1) as a molecular switch in the regulation
英文别名: JUN (Activator Protein 1, AP1, AP-1, c-Jun) (AP)中文名: 中文别名: CBNumber: CB04945538 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 1 JUN (Activator Protein 1, AP1, AP-1, c-Jun) (AP)化学性质 ...
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The recruitment of GR to EBRs requires assistance from ERα and FOXA1 and is facilitated by AP1 binding within the EBRs. The GR binding to EBRs is mediated via direct protein-protein interaction between the GR DNA-binding domain and ERα. Limited mutational analyses indicate that arginine ...
One such proto-oncogene is the activator protein (AP)2 -1 family member c-Jun, which has been shown to stabilize TAp73 (26). The mammalian AP-1 proteins belong to the Jun (c-Jun, JunB, and JunD), Fos (c-Fos, FosB, Fra1, and Fra2), and closely related activating factor (ATF-...
The addition of a number of natural and synthetic polyamines significantly increased activator protein (AP1) DNA binding in nuclear extracts of murine whole brain, which occurred in a manner positively correlated with their potencies to inhibit temperature-dependent transport of [ 3H]spermidine in brai...
EPT-E11000-1 Epigentek DNMT3A Protein (10 µg) EPT-E11002-1 Epigentek TDG Protein (10 µg) EPT-E12000-1 Epigentek TET1 Protein (10 µg) EPT-E12002-1 Epigentek TET1 Protein (Active) (10 µg) EPT-E14000-1 Epigentek DNMT3B Protein (10 µg) EPT-E15000-1 Epigentek DNMT...
ZEB1 relieves a plus-end-directed microtubule-dependent kinesin motor protein (KIF13A) and a clathrin-associated adaptor protein complex subunit (AP1S2) from microRNA-dependent silencing, thereby accelerating cargo transport through the endocytic recycling and retrograde vesicular pathways, respectively. ...
JSAP1, a Novel Jun N-Terminal Protein Kinase (JNK)-Binding Protein That Functions as a Scaffold Factor in the JNK Signaling Pathway The major components of the mitogen-activated protein kinase (MAPK) cascades are MAPK, MAPK kinase (MAPKK), and MAPKK kinase (MAPKKK). Recent rapid progres......