as well as total Cre-GFP-infected cells (GFP+) were quantified using a Nikon-ECLIPSE 80i microscope with NIS-Elements, BR. 3.00 software. The percentage of differentiated cells was calculated as the number of marker-positive cells divided by the total number of DAPI- or GFP-positive ...
Previous work has established that 60-80% of breast cancer cases exhibit abnormal PELP1 expression, which is a predictor of poorer patient outcomes2,3,22. PELP1 dysregulation is also implicated in resistance to hormone therapy in breast cancers that are positive for ER expression2,23,24,25. ...
80 60 40 20 0 Untreated HU MMS MG132 Mrc1-CFP 100 Co-localizing Not co-localizing 80 60 40 20 0 Untreated HU MMS MG132 YFP Bright field P < 0.0001 5 4 3 2 1 0 Mrc1Mrc1AQ P < 0.001 80 60 40 20 0 Mrc1Mrc1AQ Bright field YFP Bright field YFP 0.05% MMS, 2 h 75 μg ml...