VZV particles are spherical, with a diameter of 180–200 nm. Its genome is approximately 125,000 bp long, including at least 71 open reading frames. The envelope is covered with a variety of glycoproteins, some of which share functions with HSV. The known glycoproteins include gE, gB, gH,...
Molecular Genetic Insights Into Varicella Zoster Virus (VZV), the vOka Vaccine Strain, and the Pathogenesis of Latency and Reactivation. PMID: 30247591 Targeted Genome Sequencing Reveals Varicella-Zoster Virus Open Reading Frame 12 Deletion. PMID: 28747504 Antiviral Targeting of Varicella Zoster Virus Re...
PMID: 23170169 Genome-wide mutagenesis reveals that ORF7 is a novel VZV skin-tropic factor. PMID: 20617166 Varicella-zoster virus: molecular virology and virus-host interactions. PMID: 11495809 Development of recombinant varicella-zoster virus vaccines. PMID: 10599531 Genotypes of clinical varicella-...
HSV-1 transcriptome profile during lytic and latent infection. Strand-specific mRNA-seq of lytically HSV-1-infected ARPE-19 cells and seven latently HSV-1-infected human trigeminal ganglia (TG) (Supplementary Table1).aCircos plots of the HSV-1 genome [purple band; sense and antisense open rea...
Genome-wide mutagenesis reveals that ORF7 is a novel VZV skin-tropic factor. PMID: 20617166 Varicella-zoster virus: molecular virology and virus-host interactions. PMID: 11495809 Development of recombinant varicella-zoster virus vaccines. PMID: 10599531 Genotypes of clinical varicella-zoster virus isolat...
despite enclosing a genome that is substantially smaller than those of other human herpesviruses, VZV has a similarly sized capsid, consisting of 955 major capsid protein (MCP), 900 small capsid protein (SCP), 640 triplex dimer (Tri2) and 320 triplex monomer (Tri1) subunits. The VZV capsid...
infection Development and characterization of ORF68 negative equine herpes virus type-1, Ab4p strain. PMID: 30165189Kaposi's Sarcoma-Associated Herpesvirus ORF68 Is a DNA Binding Protein Required for Viral Genome Cleavage and Packaging. PMID: 29875246Characterization of Bombyx mori nucleopolyhedrovirus ...
Genome-wide mutagenesis reveals that ORF7 is a novel VZV skin-tropic factor. PMID: 20617166 Varicella-zoster virus: molecular virology and virus-host interactions. PMID: 11495809 Development of recombinant varicella-zoster virus vaccines. PMID: 10599531 ...
(AAs) that is encoded by ORF 68, which is found in the unique short region of the genome. The N-terminus of the protein consists of a hydrophilic extracellular domain (AAs 1–544) with a signal peptide (AAs 1–37), a 17 AA transmembrane hydrophobic region, and a 62 AA cytoplasmic ...
Genome-wide mutagenesis reveals that ORF7 is a novel VZV skin-tropic factor. PMID: 20617166 Varicella-zoster virus: molecular virology and virus-host interactions. PMID: 11495809 Development of recombinant varicella-zoster virus vaccines. PMID: 10599531 ...