vtRNA2–1epigeneticsDNA methylationnon-coding RNANon-coding 886 (nc886, vtRNA2鈥 1) is the only human polymorphically imprinted gene, in which the methylation status is not determined by genetics. Existing literature regarding the establishment, stability and consequences of the methylation pattern,...
Non-coding 886 (nc886, vtRNA2–1) is the only human polymorphically imprinted gene, in which the methylation status is not determined by genetics. Existing literature regarding the establishment, stability and consequences of the methylation pattern, as well as the nature and function of the nc...
cqvip:目的:检测系统性红斑狼疮(systemic lupus erythematosus,SLE)患者中T和B淋巴细胞中穹窿核糖核酸2-1(vault ribonucleic acid 2-1,VTRNA2-1)基因的表达水平,初步探索SLE的发病机制。方法:收集25例健康对照者和32例SLE患者的外周血CD4^+T淋巴细胞,另外再收集62例SLE患者(其中活动性SLE患者...
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Using another public dataset (GES89852), we found that the differential hypermethylation of the VTRNA2-1 promoter was also significantly associated with tumor recurrence. CONCLUSIONS :Patients had unfavourable outcomes when the VTRNA2-1 promoter was differentially hypermethylated in tumor tissues ...